Adverse drug reaction (ADR) is one of the most life threatening problems, and the economic burden of ADR is considerable. The main objective of this study was to assess the attitude of the Kerman health system staff, to evaluate their knowledge of the spontaneous reporting system and to identify the reasons for low reporting rate. In this descriptive study, a Persian translated questio...

background: the reporting of adverse drug reactions (adrs) by nurses in hospitals is very important.aims: this study was aimed at investigating the impact of an educational intervention to improve adr reporting and whethertrained nurses had better knowledge, attitude, and practice toward adr reporting. materials and methods: a total of 300 nurses in a tertiary care teaching hospital in tehran, ...

background: s. alopecuroides, z. officinale and m. officinalis are used traditionally in the treatment of pain. objective: to evaluate the plants effects in the rat formalin test and their activity on the opioid receptors. methods: each rat was placed individually in a cage for 30 min to get acclimated. then 0.05 ml of 10% formalin was injected subcutaneously into the dorsal surface of the righ...

thrombolytic agents are among the medications that are used widely for the treatment of thromboembolic disorders and myocardial infarction (mi). despite the world-wide availability of newer specific agents, streptokinase (sk) is still the most frequently used medication from this class in iran. hence we conducted this study to review the adverse reactions to this medication which were reported ...

Pharmacovigilance is a method of quick detection and reporting, of adverse drug reactions and adverse drug events after drug is in clinical use, thus preventing major drug events. Ignorance of physicians in developing world, about reporting adverse drug reaction is a big roadblock to pharmacovigilance. This cascades into many problems e.g.; increased lab to clinic interval, increased premarketi...

We conducted pharmacovigilance data mining for a β-lactam antibiotics, amoxicillin, and compare the adverse events (AEs) with the drug labels of 9 countries including Korea, USA, UK, Japan, Germany, Swiss, Italy, France, and Laos. We used the Korea Adverse Event Reporting System (KAERS) database, a nationwide database of AE reports, between December 1988 and June 2014. Frequentist and Bayesian ...