نتایج جستجو برای: adverse drug effect
تعداد نتایج: 2231578 فیلتر نتایج به سال:
background pharmacovigilance (pv) data are crucial for ensuring safety and effectiveness of medicines after drugs have been granted marketing approval. this paper describes the pv systems of india, uganda and south africa based on literature and key informant (ki) interviews and compares them with the world health organization’s (who’s) minimum pv requirements for a functional national pv syste...
Here in this paper, we report a 31-year-old case admitted with symptoms of hyperthyroidism that was then diagnosed with Grave's disease (GD) and underwent treatments with a low dosage of methimazole (10 mg/day). 20 days after treatments initiations, she developed antithyroid arthritis syndrome. This patient experienced arthritis and arthralgia in at least 4 joints. And all autoimmune and microb...
BACKGROUND Drug-target identification is crucial to discover novel applications for existing drugs and provide more insights about mechanisms of biological actions, such as adverse drug effects (ADEs). Computational methods along with the integration of current big data sources provide a useful framework for drug-target and drug-adverse effect discovery. RESULTS In this article, we propose a ...
Background: Cutaneous drug reaction is a common side effect of antiepileptic drugs (AEDs). In recent years, a significant increase in cases of cutaneous drug reaction due to AEDs and some changes in its pattern in our department have been noticed. Therefore, we carried out this study to present clinical and paraclinical characteristics of these cases. Methods: All records of patients who were h...
background: pain adversely affects cancer patients quality of life . knowing different sources of pain helps physicians and patients to manage it. the aim of this study was investigating physical factors affecting pain in iranian cancer patients. method: this cross-sectional study randomly enrolled cancer patients who were newly admitted to the medical oncology department of cancer institute of...
â background propofol is used as a sedative drug during colonoscopy. in this study we analyzed the adverse effects of propofol (i.e., hemodyânamic and respiratory) on patients who underwent colonoscopies. me t hod s this study was performed in qom province, iran. in this study, 125 patients (63 females, 62 males) were enrolled. study patients were administered (0.5-1.5 mg/kg) intravenous prop...
to inform healthcare professionals of a rare serious reaction leading to leg amputation following intramuscular injection of iron dextran and report comments for preventing such reactions.a case of leg amputation following intramuscular injection of iron dextran reported to iranian pharmacovigilance center was reviewed. patient and reaction data was collected by assessing the reported yellow ca...
this cross sectional study was carried out between 1993 to 1998 at razi skin hospital, the affiliated dermatology department of tehran university of medical sciences. eight hundred patients receiving etretinate for various skin diseases took part in this study. among them, 457 patients with first admission to dermatologic clinic who had at least four regular sequential visits and responding to ...
background: adverse drug reactions (adrs) are one of the leading causes of morbidity and mortality and contribute to excessive health care costs. detection and reporting of adrs could decrease these consequences. the present study was designed to assess the knowledge, attitude and practice (kap) of pharmacy students towards adrs monitoring and reporting. methods: a questionnaire was prepared to...
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