In pregnancy, resistance of endometrial decidual cells to stress signals is critical for the integrity of the fetomaternal interface and, by extension, survival of the conceptus. O-GlcNAcylation is an essential posttranslational modification that links glucose sensing to cellular stress resistance. Unexpectedly, decidualization of primary endometrial stromal cells (EnSCs) was associated with a ...

Background: Type 2 diabetes mellitus (T2DM) is non-insulin-dependent or that affects adults, and it represents 90% of diabetics occurs as a result insulin resistance defect in production. We aimed to evaluate levels adropin, insulin, lipid profile type2 patients.
 Aim: The current study investigate the relationship between type liver adipose tissue by measuring level secreted Hepatokines n...

Bu çalışmada adropin ve speksin peptitlerinin siklooksijenaz (COX) araşidonat lipooksijenaz (ALOX) gen ekspresyonları üzerindeki etkisinin kronik renal yetmezlik ekseninde gelişen kardiyak hasarda incelenmesi amaçlanmıştır.
 Sıçanlarda Kronik Renal Yetmezlik (KRY) modeli 10 gün boyunca adenin hemisülfat çözeltisinin gavaj yoluyla verilmesiyle oluşturulmuştur. Speksin tedavisi için 35 µg/kg...

Background: Flow-mediated dilation (FMD) is a noninvasive approach to examine endothelial function. Objectives: The purpose of this study was investigate the effect 12 weeks high-intensity interval training (HIIT) on FMD and circulating levels adropin nitric oxide (NO) in females with type 2 diabetes. Methods: Thirty diabetes were randomly assigned into two equal groups HIIT control. exercise p...

Purpose: Polycystic Ovary Syndrome (PCOS) is related to metabolic diseases such as endothelial dysfunction, systemic inflammation, insülin resistance and dyslipidemia. Adropin a peptide secretion that positively affects glucose homeostasis hepatic steatosis in patients with PCOS. Lipocalin-2 mediates obesity, insulin resistance, apoptosis induced by IL-3. The levels of adropin lipocalin-2 PCOS ...