Drugs that produce responses by interacting with adrenoceptors are referred to as adrenoceptor agonists or adrenergic agonists. Norepinephrine and isoproterenol are examples of such compounds. Agents that inhibit responses mediated by adrenoceptor activation are known as adrenoceptor antagonists, adrenergic antagonists, or adrenergic blocking agents. Prazosin and propranolol are examples of rec...

288 Communications to the Editor food should interfere with nitrate effects.’ Recent hemodynamic studies in coronary patients indicate increased cardiac and stroke index without changes in mean arterial or pulmonary wedge pressures, which is consistent with the effect of food on STI in our Previous studies of normal conscious dogs were also in agreement, indicating an enhanced inotropic state d...

288 Communications to the Editor food should interfere with nitrate effects.’ Recent hemodynamic studies in coronary patients indicate increased cardiac and stroke index without changes in mean arterial or pulmonary wedge pressures, which is consistent with the effect of food on STI in our Previous studies of normal conscious dogs were also in agreement, indicating an enhanced inotropic state d...

To determine the site and possible mechanism of action of adrenergic agents in regulating intraocular pressure, experiments were undertaken to identify, localize, and characterize beta-adrenergic receptors associated with adenylate cyclase in various ocular tissues involved in secretion and reabsorption of aqueous humor. The ciliary process epithelium was found to be enriched in an adenylate cy...

288 Communications to the Editor food should interfere with nitrate effects.’ Recent hemodynamic studies in coronary patients indicate increased cardiac and stroke index without changes in mean arterial or pulmonary wedge pressures, which is consistent with the effect of food on STI in our Previous studies of normal conscious dogs were also in agreement, indicating an enhanced inotropic state d...

T HE endogenously released neurotransmitter substance, norepinephrine, or an injected sympathomimetic amine, ultimately exerts its actions on an organ system by combining with an area of the effector cell termed the adrenergic “receptor site.” That drugs and neural chemical mediators react with specific receptors in living tissues was suggested by Langley”” in 1905, who suggested that effector ...