of a Dissertation Su bmitt ed i n partial fulfilment of t he requirements fo r t he degree of Doctor of Philosophy i30 STON UNI VEI10ITY GllADU AT,t; .SCHOOL

• The concept of an endocrine relationship between adrenals and kidneys has recently received considerable support. Adrenalectomy causes an increase in granularity of the juxtaglomerular cells and in pressor substances contained in kidneys; desoxycorticosterone has the opposite effects while cortisone and cortisol are reported, without supporting data, to have no effects.' It is not clear what ...

The adrenal glands are comprised of two distinct endocrine organs: the outer cortex, which is derived from mesoderm and synthesizes steroid hormones, and the inner medulla, which contains neuroectodermal cells derived from the neural crest and produces the catecholamine hormones norepinephrine and epinephrine. The developmental program that gives rise to the adrenal gland begins early during em...

Comparison of electron spin resonance signals of mitochondria, microsomes, and mitochondrial subfractions from the bovine adrenal cortex with the signals from rabbit liver microsomes have been made at temperatures near that of liquid helium. No evidence for the existence of an iron protein with g = 1.94 in liver microsomes could be obtained, whereas the presence of this component in adrenal cor...

Mitochondrial dynamics plays a significant role in shaping the mitochondrial network and maintaining function. Imbalanced can cause dysfunction leading to wide range of diseases/disorders. The aim this study was investigate expression markers regulatory molecules whole adrenal glands, cortices, medullae obtained from adult male rats exposed acute repeated psychophysical stress, most common stre...

In another paper the remarkable effect of pyogenic infections on the adrenal cortex is reviewed (1). The hypertrophy of the adrenal cortex found in chronic infections may reasonably be interpreted as due to an increased demand made upon the physiological function of that tissue. The characteristic lipoids in the cells of the cortex which are present even in complete fasting rapidly disappear in...

In the thesis describes a material on morphology of adrenal cortex cattle in postnatal develop-ment. Installed topographic features zone and cells, their comparative growth patterns under influence preparations based bioelements.

Endogenous opioid peptides are involved in the regulation of the HPA-axis function and stress response mechanism. However, there is a scarcity of data on opioid involvement in the regulation of the adrenocortical endocrine function. This study was performed to: 1) establish the expression of proenkephalin, POMC and prodynorphin genes in the porcine adrenal cortex and test in vitro the influence...