نتایج جستجو برای: adiporon

تعداد نتایج: 41  

Journal: :Journal of Cellular Physiology 2021

Iron overload (IO) is a common yet underappreciated finding in metabolic syndrome (MetS) patients. With the prevalence of MetS continuing to rise, it imperative further elucidate cellular mechanisms leading dysfunction. Adiponectin has many beneficial effects and therapeutic target for treatment cardiovascular diseases. IO positively correlates with reduced circulating adiponectin levels impact...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2017
Lei Sun Xiaoxiao Yang Qi Li Peng Zeng Ying Liu Lipei Liu Yuanli Chen Miao Yu Chuanrui Ma Xiaoju Li Yan Li Rongxin Zhang Yan Zhu Qing Robert Miao Jihong Han Yajun Duan

OBJECTIVE The reduced adiponectin levels are associated with atherosclerosis. Adiponectin exerts its functions by activating adiponectin receptor (AdipoR). Proprotein convertase subtilisin kexin type 9 (PCSK9) degrades LDLR protein (low-density lipoprotein receptor) to increase serum LDL-cholesterol levels. PCSK9 expression can be regulated by PPARγ (peroxisome proliferator-activated receptor γ...

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