Attention deficit/ hyperactivity disorder (ADHD) is a heritable neurodevelopmental disorder featuring complex genetics with common and rare variants contributing to disease risk. In a high proportion of cases, ADHD does not remit during adolescence but persists into adulthood. Several studies suggest that NOS1, encoding nitric oxide synthase I, producing the gaseous neurotransmitter NO, is a ca...

INTRODUCTION Attention-deficit/hyperactivity disorder (ADHD) is the most common childhood psychiatric disorder. This disorder is more prevalent in some chronic diseases. OBJECTIVES To investigate ADHD in children with overactive bladder. PATIENTS AND METHODS A number of 92 children with overactive bladder and 92 healthy children without overactive bladder (age range of both groups 5 to 12 y...

BACKGROUND The unique phenotypic and genetic aspects of obsessive-compulsive (OCD) and attention-deficit/hyperactivity disorder (ADHD) among individuals with Tourette syndrome (TS) are not well characterized. Here, we examine symptom patterns and heritability of OCD and ADHD in TS families. METHOD OCD and ADHD symptom patterns were examined in TS patients and their family members (N = 3494) u...

introduction: attention deficit hyperactivity disorder (adhd) is the most common psychiatric disorder in school age children and has a negative effect on the individual’s general functions. the purpose of this study was to estimate the prevalence of adhd in preschool 6 year old children in yazd in 2005 and the influence of gender, birth weight, birth order and parental education on adhd. method...

Telomere length (TL) is highly heritable, and a shorter telomere at birth may increase the risk of age-related problems. Additionally, a shorter TL may represent a biomarker of chronic stress and has been associated with psychiatric disorders. However, no study has explored whether there is an association between TL and the symptoms of one of the most common neurodevelopmental disorders in chil...

Serotonin plays an essential role in cognition, locomotor activity, and the regulation of sleep, pain, mood, and aggression. Polymorphisms of the HTR1B gene have been implicated in a variety of psychiatric disorders including attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). The objectives of this study were to: (i) expand our original investigation of the...

The behavioral difficulties of children with attention-deficit/hyperactivity disorder (ADHD) inattentive type differ from those of children with ADHD combined or hyperactive/impulsive type. Existing evidence-based interventions primarily target the disruptive and impulsive behaviors exhibited by children with ADHD combined and hyperactive/impulsive type. A number of recent advances have been ma...

STUDY OBJECTIVES Children with attention-deficit/hyperactive disorder (ADHD), in spite of being hyperactive, still benefit from treatment with stimulant medications. We hypothesized that children with ADHD are in fact sleepy during the day, and we sought to test it objectively. DESIGN Single blind comparative study SETTING University medical center PARTICIPANTS Thirty-four children with a...

OBJECTIVES Adults with attention-deficit hyperactive disorder (ADHD) report high rates of comorbid disorders, educational and occupational failure, and family instability. The aim of this study was to examine the prevalence of comorbid psychiatric disorders in a clinical population of adults with ADHD and to examine associations between educational level, work participation, social characterist...

Background. A relationship between attention deficit hyperactivity disorder (ADHD) and obesity has been consistently documented. Obesity metabolic syndrome have associated with misalignment daily activities circadian rhythm. ADHD patients a high prevalence of delayed sleep phase syndrome, which is rhythm disorder. Understanding this important for the evaluation obese population at risk. Objecti...