Acute disseminated encephalomyelitis (ADEM) is an acute demyelinating disease occurring 1–3 wk after viral infection or vaccination1,2. Although most patients with ADEM make a full recovery, corticosteroids can be of help in severe cases. Generally, the diagnosis of ADEM is made by clinical history, neurological manifestations and magnetic resonance images (MRI) of the central nervous system. N...

The proof follows from relations between Adem relations (4), using what Bousfield calls “pension operators”, i.e. selfmaps of tensor powers which preserve Adem relations. I believe Bousfield had a proof of this sort. Following Mahowald’s suggestion, we’ll give an EHP proof of the basis. Let V be the Z/2 vectorspace with basis {λp : p ≥ −1}. Define e : V → V by e(λp) = λp+1, and define the selfm...

PURPOSE Acute disseminated encephalomyelitis (ADEM) is a monophasic demyelination disease of central nervous system (CNS) with presentations of impaired consciousness, neurologic deficits and diffuse white matter lesions on magnetic resonance imaging (MRI). Predisposing infection can be identified in around 50 to 77% of all patients with ADEM. Post-infectious autoimmune events associated with J...

Objective. To describe the epidemiologic, clinical, neuroimaging, and laboratory features; treatment; and outcome in a cohort of children with acute disseminated encephalomyelitis (ADEM). Methods. A 6-year retrospective chart review of children with the diagnosis of ADEM was conducted. Results. Eighteen cases were identified. Sixteen patients (88%) presented in either winter or spring. Thirteen...

BACKGROUND Sixth (abducens) nerve palsy (ANP) is far less frequent in children and has not been reported as a sign of acute disseminated encephalomyelitis (ADEM). We present an infant case of ADEM with bilateral abducens nerve palsy (BANP). CASE PRESENTATION We report one case of BANP in a 15-month-old boy of fulminant ADEM. The patient underwent physical examinations and brain MRI scan three...

BACKGROUND Some pediatric patients with inflammatory demyelinating central nervous system disorders cannot be classified under any of the established disease entities, making their treatment and prognosis difficult. OBJECTIVE The objective of this study is to characterize a subgroup of pediatric patients with recurrent demyelinating central nervous system disorders. METHODS This study inclu...

abstract acute disseminated encephalomyelitis (adem) is a rare immune mediated and demyelinating disease of the central nervous system that usually affects children. it as a monophasic disorder related with multifocal neurologic symptoms. here in this paper we report seven cases of adem in pediatrics and besides a review of literatures are presented.

BACKGROUND AND PURPOSE Patients with acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) have a similar pattern of abnormalities on conventional MR images. We used magnetization transfer and diffusion tensor MR imaging to quantify normal-appearing brain tissue and cervical cord disease in patients with ADEM and to compare findings with those in healthy volunteers and patient...

OBJECTIVE To evaluate epidemiological features of post vaccine acute disseminated encephalomyelitis (ADEM) by considering data from different pharmacovigilance surveillance systems. METHODS The Vaccine Adverse Event Reporting System (VAERS) database and the EudraVigilance post-authorisation module (EVPM) were searched to identify post vaccine ADEM cases. Epidemiological features including sex...

Acute disseminated encephalomyelitis (ADEM) is an autoimmune demyelinating disorder of the central nervous system and can present following influenza A infections as multifocal neurological deficits. ADEM remains a challenging diagnosis, and high clinical suspicious coupled with laboratory investigations and neuroimaging is required to exclude other primary and secondary demyelinating disorders.