Toxoplasma infection in pregnant women may cause congenital toxoplasmosis. Diagnosis of infection is based on serological tests aimed at detecting IgM and IgG antibodies against Toxoplasma gondii. However, IgM antibodies are not an accurate marker for discriminating between acute and latent infection. Detection of residual or persistent IgM may occur months or even years after primary infection...

BACKGROUND The prevalence of Toxoplasma gondii infection in the blood donors has been poorly studied. The aim of this study was to assess the prevalence of acute and chronic toxoplasmosis in blood products. METHODS A total of 250 blood products (112 fresh frozen plasma and 138 packed cells) in the Blood Transfusion Institute, Shiraz, Iran were tested for specific T. gondii antibodies (IgG and...

Toxoplasmosis is caused by infection with the protozoan parasite Toxoplasma gondii. In the United States, approximately 85% of women of childbearing age are susceptible to acute infection with T. gondii. Acute infections in pregnant women may cause serious health problems when the organism is transmitted to the fetus (congenital toxoplasmosis), including mental retardation, seizures, blindness,...

BACKGROUND Toxoplasmosis is one of the most common human zoonosis, and is generally benign in most of the individuals. Pulmonary involvement is common in immunocompromised subjects, but very rare in immunocompetents and there are scarce reports of tomographic findings in the literature. The aim of the study is to describe three immunocompetent patients diagnosed with acute pulmonary toxoplasmos...

On the basis that 89% of 48 acute-phase toxoplasmosis patients showed immunoglobulin M (IgM) class antibodies to the 35,000-molecular-weight antigenic component (p35000) of Toxoplasma gondii, as demonstrated by IgM immunoblotting, the antigen was purified by sucrose gradient centrifugation and enzyme labeled for use in an enzyme-linked antigen immunosorbent assay (ELA) for the demonstration of ...

BACKGROUND In immunocompetent patients, acute toxoplasmosis is usually asymptomatic. We identified M1 macrophages in a case of symptomatic acute Toxoplasma gondii infection that resolved without treatment. M1 macrophages have been demonstrated in animal models of toxoplasmosis, but not in humans. CASE PRESENTATION A 63-year-old woman presented with laterocervical and axillary bilateral lympha...

An epizootic of toxoplasmosis occurred among 22 adult and 30 kit black-footed ferrets (Mustela nigripes) maintained under quarantine conditions at the Louisville Zoological Garden (Louisville, Kentucky, USA) in June, 1992. Black-footed ferrets appear to be highly susceptible to acute and chronic toxoplasmosis. Clinical signs were observed in 19 adults and six kits and included anorexia, letharg...

The influence of latent toxoplasmosis on the phenotype , especially on the behaviour, of intermediate hosts has been intensively studied since the mid-1990s. The number of papers dealing with this topic that can be found in the Web of Knowledge SM by using the combination of terms toxoplasm* AND (behavi* OR psychol* OR per-sonalit* OR psychiatri* OR schizophr*) is rapidly in-Most of these paper...

Toxoplasmosis is one of the most prevalent parasitic infections common among humans and animals having two acute and chronic phases related to IgM and IgG, respectively. Immunoblotting is one of the serological methods with high sensitivity and specificity. Therefore, the present study aims to evaluate T. gondii RH strain antigen using the Western blot assay, their applications to distinguish b...

background: toxoplasma specific igm antibodies; the common serologic marker in diagnosis of acute toxoplasmosis has its own limitations. confirmatory testing with other markers, introduced as a complementary tool in distinguish acute and chronic infections is unusual in iran. in the present study, we investigated the cor-relation between the results of igm elisa, iga elisa, and igg avidity test...