vitamin e is a potent reactive oxygen metabolites (rom) scavenger. it is a lipid-soluble vitamin and its main function is to protect polyunsaturated fatty acids against oxidative stress. twenty-five mechanically ventilated intensive care unit (icu) adult patients participated in a prospective randomized clinical trial receiving either placebo (10 patients) or 3 im doses (1000 iu each) of vitami...

OBJECTIVE To evaluate the clinical characteristics and costs incurred for patients who stayed for a prolonged period in a surgical intensive care unit (ICU). DESIGN AND METHODS Data of all patients admitted to a surgical ICU in Barbados during the period of two years from July 1999 to June 2001 were prospectively collected. Demographic data, diagnoses on admission and Acute Physiology and Chr...

BACKGROUND Mortality predictions calculated using scoring scales are often not accurate in populations other than those in which the scales were developed because of differences in case-mix. The present study investigates the effect of first-level customization, using a logistic regression technique, on discrimination and calibration of the Acute Physiology and Chronic Health Evaluation (APACHE...

The Acute Physiology and Chronic Health Evaluation System (APACHE II) was used in 451 patients admitted to the intensive care unit, Belfast City Hospital, in 1988 and 1989. Mortality in the patients studied was 15.5% which is slightly less than that predicted for patients with equal severity of disease (18.8%). Within the limitations discussed the APACHE II system has valuable potential both in...

conclusions a slightly higher mortality in patients with pneumonia, caused by s. maltophilia, was strived to explain by advanced age, higher acute physiology and chronic health evaluation (apache ii) and sepsis related organ failure assessment (sofa) score, and also higher inappropriate antibiotic use. results a total of 71 patients with s. maltophilia nosocomial infections, 35 (49.3%) primary ...

This article describes the potential for the acute physiology score (APS) of acute physiology and chronic health evaluation (APACHE) II, to be used as a severity adjustment to diagnosis-related groups (DRG's) or other diagnostic classifications. The APS is defined by a relative value scale applied to 12 objective physiologic variables routinely measured on most hospitalized patients shortly aft...

BACKGROUND Intensive care unit survivors often have diminished health-related quality of life. OBJECTIVES To describe health-related quality of life of former intensive care patients and identify associated factors 6 months after hospital discharge. METHODS Six months after discharge, 193 patients from an intensive care unit completed the Short Form-36 Health Survey; measures of sleep; Inte...

The acute physiology and chronic health evaluation (APACHE II) 1 is a scoring system that provides a means for describing and predicting acute illness severity over a broad range of intensive care unit (ICU) patients 1-3 . Clinical investigators commonly use the APACHE II score in their research protocols to identify differences between treatment groups 4 . Severity scoring systems, such as the...