CONTEXT Pancreatic adenocarcinoma presenting as idiopathic thrombocytopenic purpura has not been previously reported in the literature. CASE REPORT A newly diagnosed patient with metastatic pancreatic adenocarcinoma developed thrombocytopenic purpura prior to initiation of chemotherapy. Generalized petechiae were present and peripheral smear revealed giant platelets. Drug induced and other th...

In idiopathic thrombocytopenic purpura (ITP), a quite prevalent autoimmune hematological disease, thrombocytopenia is observed because of platelet destruction caused by immunological mechanisms. ITP usually leads to bleeding. Nevertheless, ITP, although rarely observed, may lead to thrombotic complications, including ischemic stroke. The present case is a female patient with ITP who developed c...

Idiopathic thrombocytopenic purpura (ITP) is an immune-mediated thrombocytopenia. ITP is the result of accelerated platelet destruction by the reticuloendothelial system, primarily the spleen. The prevalence of Helicobacter pylori infection and the effect of its eradication were monitored in an ITP patient over a period of 12 months. Eradication of Helicobacter pylori led to the increased plate...

A CAUSAL ASSOCIATION BETWEEN MEASLES: mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vacci...

Women with idiopathic thrombocytopenic purpura (ITP) may become pregnant, or the disease may occur for the first time during pregnancy. Thrombocytopenia is usually noticed in the first months of pregnancy and the platelet count is often quite low. In this case report, we described the anaesthetic method for caesarean section in a pregnant woman at 38 weeks of gestation with refractory ITP.

background: idiopathic thrombocytopenic purpura is an autoimmune blood disorder in which platelet destruction is mediated by anti-platelet antibodies. there are two forms of itp: acute and chronic. the aim of the present study was to evaluate the clinical variables in adult patients with acute itp in west of iran. patients and methods: medical records of adult patients with diagnosis of acute i...

Abbreviations: acute myeloid leukemia, (AML); American Society of Clinical Oncology, (ASCO); bone marrow, (BM); end stage renal disease, (ESRD); erythropoietin, (EPO); granulocyte colony-stimulating factor, (G-CSF); Granulocyte-macrophage colony-stimulating factor, (GM-CSF); hematopoietic growth factors, (HGFs); hematopoietic stem cell, (HSC); hemoglobin, (Hgb); idiopathic thrombocytopenic purp...

Idiopathic thrombocytopenic purpura (ITP) with HELLP represents a rare complication that requires combined care of obstetrician, anesthesiologist, hematologist, and neonatologist. At 37-week gestation a 35-year-old parturient (G2A1P0) a known case of chronic ITP presented with severe pregnancy induced hypertension (PIH), thrombocytopenia, and elevated liver enzymes. We describe successful anest...

First-line therapies of acute and chronic idiopathic thrombocytopenic purpura (ITP) include intravenous immunoglobulin, IV anti-D and corticosteroids. A short-course high-dose dexamethasone (HDD-SC) therapy has recently been reported to be efficacious in acute ITP. The present study was conducted to assess the efficacy of HDD-SC in children with chronic ITP. Over a period of 10 months, 13 patie...

hepatitis a is common in children and usually is a self-limiting disease.  although extrahepatic and hematological immune manifestations following acute hepatitis a virus (hav) infection have rarely been reported, they are frequently observed in other viral hepatitis. in this paper, we report the case of a 3-year-old girl who developed immune thrombocytopenic purpura (itp) and hemolytic anemia ...