Children with kwashiorkor almost invariably have diarrhoea which may be severe and prolonged. The exact cause is often obscure and the management unsatisfactory (Brock et al., 1955; Trowell, 1958; Pretorius and Smit, 1958). Recently Bowie, Brinkman, and Hansen (1965), and Bowie, Barbezat, and Hansen (1967) found that the majority of their kwashiorkor patients with severe diarrhoea responded wit...

OBJECTIVE To determine if educating caregivers in providing zinc supplements to infants < 6 months old with acute diarrhoea is effective in treating diarrhoea and preventing acute lower respiratory infections (ALRIs), and whether it leads to a decrease in the use of oral rehydration salts (ORS). METHODS In this retrospective subgroup analysis of infants aged < 6 months, six clusters were rand...

OBJECTIVE To evaluate the effect on morbidity and mortality of providing daily zinc for 14 days to children with diarrhoea. DESIGN Cluster randomised comparison. SETTING Matlab field site of International Center for Diarrhoeal Disease Research, Bangladesh. PARTICIPANTS 8070 children aged 3-59 months contributed 11 881 child years of observation during a two year period. INTERVENTION Chi...

Firstly, the planners, the economists, the actuaries, and the lawyers have to sit down with tne doctors and devise a new format, shorn of expensive bureaucracy, which is more efficient, competitive, and, in the long run, cheaper. This then has to be sold up-hill to those who will fear losing their mess of pottage in any transition, and this would obviously mean many of the senior doctors approa...

Persistent diarrhoea is an important cause of illness and death in children in developing countries. Moreover, as acute diarrhoea is more widely and successfully treated with oral rehydration therapy (ORT), the proportion of diarrhoea deaths associated with persistent diarrhoea will probably increase. In the mid1980s the World Health Organization recognised that efforts to control persistent di...

The three most important infectious diseases of young children in Papua New Guinea are acute lower respiratory tract infections, diarrhoea and malaria, each of which has been shown to have a negative effect on growth. Low nutritional status is associated with increased risk and severity of acute lower respiratory tract infections and with increased severity of diarrhoea. There is no evidence to...