Generic and brand name antiretroviral drugs are becoming increasingly available in developing countries. We analyzed 6 antiretroviral medications from 4 international sources for drug content. The active ingredient in tested drug products was within 15% of the labeled amount (range, -12% to +15%) for drugs that were properly stored.

Strain BCT-7112, previously identified as Bacillus cereus var. toyoi, is the type strain of the species Bacillus toyonensis, a novel species of the B. cereus group. The complete genome of this strain, which is the active ingredient of the feed additive preparation Toyocerin, has been sequenced and annotated to reveal the genetic properties of this probiotic organism with a long history of safe ...

The initial soil penetration of Premise 75 and Termidor SC, containing imidacloprid and fipronil, respectively, were tested in laboratory columns of five different soils. Three combinations of application concentration and volume were used: double the recommended active ingredient concentration at one half the recommended volume (DR), the full concentration and volume (FR), and one half the con...

A new chemical compound was tested for its insecticidal activity against several major insect pests. The compound, called "flufenerim", has a core pyrimidine structure and an unknown mode of action and showed potent activity against the sweet potato whitefly Bemisia tabaci (Gennadius), the green peach aphid Myzus persicae (Sulzer), and the African cotton leafworm Spodoptera littoralis (Boisduva...

Controlled release drug delivery systems 1 are those dosage formulations designed to release an active ingredient at rates, which differ significantly from their corresponding conventional dosage forms. The controlled release drug delivery systems are aimed at controlling the rate of drug delivery, sustaining the duration of therapeutic activity and/or targeting the delivery of the drug to a ti...

BACKGROUND TO THE DEBATE The UK Medical Research Council defines complex interventions as those comprising "a number of separate elements which seem essential to the proper functioning of the interventions although the 'active ingredient' of the intervention that is effective is difficult to specify." A typical example is specialist care on a stroke unit, which involves a wide range of health p...

A water-soluble chicken extract is popularly consumed as a traditional health food. The studies made revealed that it could increase the survival time and inhibit the increase of locomotor activity in rats loaded with food-deprived activity stress. The mechanism for this might be related to an elevation of the brain histamine level, and the active ingredient, carnosine, might contribute to this...

Larvae of Culex pipiens and Cx. restuans in catch basins were exposed to Altosid pellets (4% active ingredient, [S]-methoprene) applied at a rate of 11.3 kg/ha (7 g of pellets per catch basin). Under field conditions, the pellets yielded an average 82% emergence inhibition of adult mosquitoes over the 15-wk trial period.