Genetic studies of the determination of Salmonella flagella have suggested that the alternative antigenic phases correspond to two distinct homology groups, i.e., to factors at two distinct genetic loci, one for phase 1 ("specific phase"), and one for phase 2 ("group phase") (Lederberg and Edwards, 1953). It has, however, been generally understood that the two phases were equivalent to one anot...

mechanisms which prevent formation of infective T2H bacteriophage in T ~ c h r i c h i a coli in the presence of acridine dyes are unknown. That interruption of normal maturation occurs in a late stage of phage development was suggested by the work of FOSTER (1948) and has been substantiated physiologically and cytologically. DEMARS, LURIA, FISHER and LEVINTHAL ( 1953) and DEMARS (1955) found i...

The toxicities of several aminoacridines were measured against pathogenic strains of both Gram-positive (Staphylococcus aureus, Enterococcus faecalis, Bacillus cereus) and Gram-negative (Escherichia coli, Pseudomonas aeruginosa) organisms. In several cases, illumination at a light dose of 6.3 J/cm2 resulted in considerable decreases in the minimum lethal drug concentrations required, giving up ...

A study was made of the change's produced in action potentials of frog ventricular cells by variation in ion concentrations, by administration of NaN3, 2: 4 DNP, NaCN, NalA and N2 which shortened the potentials. The exposure of the perfused tissue to ionized acridines, barbiturates and desoxyglucose caused a prolongation of the action potentials. These actions as obtained were reversible. The e...