OBJECTIVE To evaluate the effect of sodium fluoride rinse on sucrose-induced decrease in plaque pH with interdental plaque pH telemetry. METHODS Six participants wearing partial lower prostheses incorporating a miniature glass pH electrode were included. The measurement of plaque pH was performed after 6 days of plaque accumulation. Three experiments were performed to test the effects of fluo...

The acidogenicity of Streptococcus mutans is important for caries development. antimicrobial peptide GH12 can affect the integrity cellular membranes and virulence factors S. mutans. Combining NaF (GF) efficiently controlled development caries, but its mechanisms remained unrevealed. This research intended to verify effects GF on biofilms reveal mechanisms. Lactic acid production assays pH moni...

A previous longitudinal study about using microbiome as a caries indicator has successfully predicted early childhood (ECC) in healthy individuals, but there is no evidence to verify the composition of core microbiota and its pathogenicity vitro vivo. Biofilm acidogenicity, S. mutans count, biofilm were estimated by pH evaluation, colony-forming unit, quantitative PCR, respectively. Extracellul...