A completely automated fluorometric determination of amphetamine in urine is described and evaluated. The dihydrolutidine derivative produced by reaction of amphetamine with formaldehyde and acetylacetone is excited at 410 nm and the resulting intensity of fluorescence measured at 476 nm. The working limit of detection of amphetamine in fresh urine (1.5-mi samples) is 0.15 mg/liter. A result is...

A direct seedless method for the continuous synthesis of gold nanorods has been developed using a sequential rotating tube-narrow channel processing microfluidic configuration, with the stock feed solutions (HAuCl(4)/CTAB/acetylacetone and AgNO(3)/CTAB/carbonate buffer) being stable for weeks.

New bifunctional organocatalysts amine-thioureas bearing multiple hydrogen bonding donors were synthesized and applied in catalytic asymmetric Michael addition of acetylacetone to aryl and alkyl nitroolefins. Multiple hydrogen bonding donors play a significant role in accelerating reactions, improving yields and enantioselectivities.

The paper presents an application of the asymmetry approach to spirooxindoles via Brevicolline, Cinchonidine or Cinchonine catalyzed one-pot multicomponent synthesis. Brevicolline, in comparison with Cinchonidine or Cinchonine, catalyzes the reaction of isatins, acetylacetone/ethyl 3-oxobutanoate and malononitrile, with the formation of spiro[oxindole-3,4'-4'H-pirane] derivatives in an opticall...

New bis(oxazolinyl)phenyl-ruthenium(II) complexes, which were synthesized by C-H bond activation with RuCl(3).3H(2)O in zinc powder and 1,5-cyclooctadine followed by ligand exchange reaction with sodium acetylacetonate or acetylacetone, exhibited enantioselective hydrogenation of ketones in up to 90% ee.

A simple, green synthesis of N-alkyl-3-acetyl-2-methylpyrrole derivatives using ZnO nanoparticles from the three component reaction of aliphatic amines, acetylacetone (as a 1,3-dicarbonyl compound) and α-haloketones under solvent-free condition is described.

Oxidative addition of N-(2-iodophenyl)formamide to Pd(dba)2 (dba = dibenzylideneacetone) in the presence of 4,4'-ditertbutyl-2,2'-bipyridine ((t)Bubpy) produces [Pd(C6H4NHCHO-2)I((t)Bubpy)] (1) which inserts 2-iodophenyl isocyanide to give [Pd{C(=NC6H4I-2)C6H4NHCHO-2}I((t)Bubpy)] (2). Dehydroiodination of 2 with Tl(acac) (acacH = acetylacetone) gives the stable Pd(IV) complex OC-6-35-[Pd{C,N,N-...

The co-extraction phenomenon was found in a typical chelate extraction system, in which the extraction of lanthanoid ion (Ln3+) with acetylacetone (Hacac) was highly enhanced by various metal ions (M(n+)) such as Cu2+, Al3+, and Zr4+. This phenomenon was ascribed to the formation of the 1:1 adduct between Ln(acac)3 and the M(acac),, extracted into the organic phase. The co-extraction occurred m...