Fourier transform infrared (FTIR) and gel permeation chromatography (GPC) wre respectively utilized in determining the changes in isocyanate (NCO) concentration and molecular weight (MW) and its distribution (MWD) in polyurethanes during their cure and postcure stages. Samples, originally cured at 45°C, were taken through accelerate aging tests at various temperatures. The FTIR and GPC anal...

The color properties of aging wood samples from historical buildings have been compared with those of recent wood samples that were heat treated at temperatures ranging from 90 to 180°C. The results of kinetic analysis obtained by the time-temperature superposition method showed that the color change during natural aging was mainly due to a slow and mild oxidation process. In other words, heat ...

In order to further study the effect of different degree acidity and alkalinity on cable insulation aging, aging condition was compared analyzed under pH values. The samples material slice short were carried out accelerated test, which placed in conditions And then test results micro morphology electrical properties between after aging. According this paper, would change differently alkalinity,...

Cumulative mtDNA damage occurs in aging animals, and mtDNA mutations are reported to accelerate aging in mice. We determined whether aging results in increased DNA oxidative damage and reduced mtDNA abundance and mitochondrial function in skeletal muscle of human subjects. Studies performed in 146 healthy men and women aged 18-89 yr demonstrated that mtDNA and mRNA abundance and mitochondrial A...

A valid method of studying age related degenerative pathologies is to study human genetic diseases that appear to accelerate many, though not necessarily all, features of the aging process. Such diseases are described as progeroid syndromes because of their possible relevance to many aspects of aging and age related disease. This article describes the recent progress made at the cellular and mo...

Cells are constantly exposed to a variety of environmental and endogenous conditions causing DNA damage, which is detected and repaired by conserved DNA repair pathways to maintain genomic integrity. Chromatin remodeling is critical in this process, as the organization of eukaryotic DNA into compact chromatin presents a natural barrier to all DNA-related events. Studies on human premature aging...

While murine-based systems to identify cancer-promoting agents (carcinogens) are established, models to identify compounds that promote aging (gerontogens) have not been described. For this purpose, we exploited the transcription of p16INK4a, which rises dynamically with aging and correlates with age-associated disease. Activation of p16INK4a was visualized in vivo using a murine strain that ha...

Similarly in the commercial airline industry, the global Maintenance, Repair and Overhaul (MRO) business is faced with creating total service packages to attract future work, as airlines accelerate outsourcing and retire aging aircraft to minimize life cycle and transaction costs. Third-party service providers are challenging the market share traditionally dominated by the major airline subsidi...

The quality of metaphase II oocytes will undergo a time-dependent deterioration following ovulation as the result of the oocyte aging process. In this study, we determined that the expression of sirtuin family members (SIRT1, 2, 3) was dramatically reduced in mouse oocytes aged in vivo or in vitro. Increased intracellular ROS was observed when SIRT1, 2, 3 activity was inhibited. Increased frequ...