Introduction: Visceral leishmaniasis (kala-azar) caused by Leishmania donovani and transmitted by the sand-fly Phlebotomus martini is endemic in certain foci in north-eastern Uganda where it is thought to be confined to Pokot county, Amudat district. Amudat hospital records (April 1998-March 1999) indicated that kala-azar accounted for about 17% of hospital in-patients. However the actual preva...

their spleens by " spleen puncture." Certainly, most of the patients whom we see are sent to us . from the Medical College Hospital Out-patient Dispensary and by local practitioners because they have symptoms which suggest kala-azar. On the other hand, of the patients who are eventually diagnosed kala-azar in the Medical College Hospital, more than half have been admitted not as kala-azar patie...

Since 1990, South Asia has experienced a resurgence of kala-azar (visceral leishmaniasis). To determine risk factors for kala-azar, we performed cross-sectional surveys over a 3-year period in a Bangladeshi community. By history, active case detection, and serologic screening, 155 of 2,356 residents had kala-azar with onset from 2000 to 2003. Risk was highest for persons 3-45 years of age, and ...

Objective: The diagnostic role of rK39 enzyme linked immunosorbent assay (ELISA) was compared with the buffy-coat Leishmania nested polymerase chain reaction (Ln-PCR) for kala-azar in an endemic zone of Bangladesh. Methodology: This evaluation study included 100 cases comprising of 60 clinically suspected patients of kala-azar and 40 healthy controls. Anti-rK39 antibody was estimated in plasma ...

are widespread. Some indication of the value of antimony is the fact that without treatment the death rate from kala-azar is over 90 per cent, whereas with treatment in Indian kalaazar it is reduced to below 10 per cent. Although tartar emetic was found of value in the treatment of kala-azar, its considerable toxic effects made it imperative to obtain other derivatives which should be better to...

There are few reports linking hyponatremia and visceral leishmaniasis (kala-azar). This is a study of 55 consecutive kala-azar patients and 20 normal individuals as a control group. Hyponatremia and serum hypo-osmolality were detected in 100% of kala-azar patients. High first morning urine osmolality (750.0 ± 52.0 vs. 894.5 ± 30.0mOsm/kg H₂O, p < 0.05), and high 24-hour urine osmolality (426.0 ...

مسئله جبر و اختیار از مباحث دراز دامن مهمی ‌است که دیرباز اذهان انسان‌ها را به خود معطوف کرده‌است اندیشمندان در ادیان مکاتب مختلف برابر این مسئلة حیاتی مواضعی اتخاذ کرده‌اند. اصلی مقاله آن است عامری پیرامون چه دیدگاهی کرده‌است؟ فرضیه نظریة یا مطلق دفاع نمی‌کند، بلکه راه بینابین برمی‌گزیند. اهم یافته‌های عبارت‌اند : او برای پاسخ پژوهشی ابتدا تحریر محل نزاع می‌کند میان دو حیثیت شیء اعتبار ذاتش غی...

In this study 4 patients were post-kala-azar dermal leishmaniasis (PKDL), whose lesions were similar to those of lepromatous and borderline leprosy, are described. In 2 patients there was no previous history of kala-azar but they were residents of an area of known endemic kala-azar. Lack of proper clinical and laboratory assessment was behind the failure to diagnose PKDL. Consequently the patie...

Concomitant skin lesions in visceral leishmaniasis (VL) or kala-azar are rare, being more common the description of post-kala-azar dermal leishmaniasis occurring post treatment of kala-azar. Skin lesions caused by Leishmania donovani are frequently seen in the aids-VL co-infection. In Brazil cutaneous or mucosal forms of tegumentary leishmaniasis concomitant with aids are more commonly register...

After two peaks of epidemic of Kala Azar, one in 1977 with 100,000 cases(l) and another in 1991-92 with 250,000 cases(2), the disease continues to be endemic in North Bihar The first line drug sodium antimony shbogluconate (SAG) used in the dosage of 20 mg/kg body weight daily for 30 days(3) or 40 days(4) has become less effective and a number of patients are unresponsive to the drug(5) Oral Fl...