By Susis W. FONG, ARLENE NUCKTON AND H. H. FUDENBERG M ANY SEROLOGIC tests have been advocated as aids for the antenatal diagnosis of ABO hemolytic disease of the newborn (ABO HDN). The majority of the tests currently used in most hospital clinical laboratories for this purpose make use of certain serologic properties that differentiate the isoagglutinins into two groups. Although both groups p...

Many different blood group systems, such as Rh, ABO, Kell, Kidd, Duffy, MNS, have been reported as causes of hemolytic disease of the newborn. Hemolysis due to minor blood group incompatibility in the fetus or newborn has been determined in isolated case reports. Here, we report a case of a patient who had received red cell transfusion due to severe Rh c and E incompatibility, leading to hemoly...

Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative option for a variety of malignant and non-malignant hematological and congenital diseases. Due to the fact that the human leukocyte antigen system is inherited independently of the blood group system, approximately 40-50% of all HSCTs are performed across the ABO blood group barrier. The expected immune-hematological conseq...

In the field of orofacial surgery, a red blood cell transfusion (RBCT) is occasionally required during double jaw and oral cancer surgery. However, the question remains whether the effect of RBCT during the perioperative period is beneficial or harmful. The answer to this question remains challenging. In the field of orofacial surgery, transfusion is performed for the purpose of oxygen transfer...

Wit/i the assistance of KATHRYN BEAVFIE T HE SUB.JECT of this report is an unusual experiment of nature imivolving a pair of twins of different A and B blood groups bormi to a group 0 mother. The devebopmemit of frank hemolytic disease in the twin hebongimig to blood group B, in the absence of recognizable abmiormalities imi the group A twin was the indication for a detailed study of the behavi...

INTRODUCTION Hemolytic disease of the newborn was first described in the medical literature 1609, when it was diagnosed in one French housewife. In 1932 Diamond and colleagues described the mutual relationship of fetal hydrops, jaundice, anemia and erythoblastosis, which was later called fetal erytroblastosis. Hemolytic disease of the newborn (HDN) in the strict sense is considered disease whos...