نتایج جستجو برای: abad agricultural research station

تعداد نتایج: 1519388  

Journal: :Kansas Agricultural Experiment Station Research Reports 1985

2006
Joseph DiPietro

(CASNR) dates back to 1869 when the university was designated as Tennessee’s federal land-grant institution. Under terms of the Federal Land-Grant Act, the university was enabled for the first time to offer instruction in agriculture. Later, federal legislation provided resources for agricultural research and extension programming for dissemination of research findings to the people of Tennesse...

1999
M. P. N. Gent

M. P. N. Gent, Department of Forestry and Horticulture, Connecticut Agricultural Experiment Station, New Haven 06504; J. A. LaMondia, Department of Plant Pathology and Ecology, Connecticut Agricultural Experiment Station, Windsor 06095; F. J. Ferrandino and W. H. Elmer, Department of Plant Pathology and Ecology, Connecticut Agricultural Experiment Station, New Haven 06504; and K. A. Stoner, Dep...

1997
J. S. McConnell F. M. Bourland W. H. Baker

Journal: :Science 2004
Joyce W Lustbader Maurizio Cirilli Chang Lin Hong Wei Xu Kazuhiro Takuma Ning Wang Casper Caspersen Xi Chen Susan Pollak Michael Chaney Fabrizio Trinchese Shumin Liu Frank Gunn-Moore Lih-Fen Lue Douglas G Walker Periannan Kuppusamy Zay L Zewier Ottavio Arancio David Stern Shirley ShiDu Yan Hao Wu

Mitochondrial dysfunction is a hallmark of beta-amyloid (Abeta)-induced neuronal toxicity in Alzheimer's disease (AD). Here, we demonstrate that Abeta-binding alcohol dehydrogenase (ABAD) is a direct molecular link from Abeta to mitochondrial toxicity. Abeta interacts with ABAD in the mitochondria of AD patients and transgenic mice. The crystal structure of Abeta-bound ABAD shows substantial de...

2013
Xu Wang Yi Yang Mingyue Jia Chi Ma Mingyu Wang Lihe Che Yu Yang Jiang Wu

Amyloid β peptide binding alcohol dehydrogenase (ABAD) decoy peptide (DP) can competitively antagonize binding of amyloid β peptide to ABAD and inhibit the cytotoxic effects of amyloid β peptide. Based on peptide aptamers, the present study inserted ABAD-DP into the disulfide bond of human thioredoxin (TRX) using molecular cloning technique to construct a fusion gene that can express the TRX1-A...

2015
Jian J. Duan Leah S. Bauer Kristopher J. Abell Michael D. Ulyshen Roy G. Van Driesche

associated natural enemies in the aftermath of invasion: implications for biological control Jian J. Duan*, Leah S. Bauer, Kristopher J. Abell, Michael D. Ulyshen and Roy G. Van Driesche United States Department of Agriculture, Agricultural Research Service, Beneficial Insects Introduction Research Unit, Newark, DE 19713, USA; USDA Forest Service, Northern Research Station, Lansing, MI 48910, U...

Journal: :Current Alzheimer research 2014
Koteswara R Valaasani Qinru Sun Gang Hu Jianping Li Fang Du Yaopeng Guo Emily A Carlson Xueqi Gan Shirley S Yan

Amyloid beta (Aβ) binding alcohol dehydrogenase (ABAD) is a cellular cofactor for promoting (Aβ)-mediated mitochondrial and neuronal dysfunction, and cognitive decline in transgenic Alzheimer's disease (AD) mouse models. Targeting mitochondrial ABAD may represent a novel therapeutic strategy against AD. Here, we report the biological activity of small molecule ABAD inhibitors. Using in vitro su...

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