In primary hyperparathyroidism (pHPT), parathyroidectomy is the treatment of choice, but anatomic variations of ectopic glands may cause surgical failure. Reliable preoperative noninvasive localization procedures would have a positive impact on the operative time and increase recovery rate. We retrospectively evaluated 186 patients with pHPT who were studied before successful parathyroidectomy ...

UNLABELLED The purpose of this study was to develop an in vivo imaging protocol for a high-resolution stationary SPECT system, called FASTSPECT, in a rat heart model of ischemia-reperfusion (IR) and to compare 99mTc-sestamibi imaging and triphenyltetrazolium chloride (TTC) staining for reliability and accuracy in the measurement of myocardial infarcts. METHODS FASTSPECT consists of 24 modular...

Objectives This retrospective study evaluated whether the use of additional anterior 99mTc-sestamibi/123I pinhole imaging improves the outcome of 99mTc-sestamibi/123I subtraction SPECT/CT in parathyroid scintigraphy (PS). Materials and Methods PS using simultaneous dual-isotope subtraction methods and an acquisition protocol combining SPECT/CT and planar pinhole imaging was performed for 175 ...

The whole-body and hand radiation doses to our technical staff were retrospectively compared for three distinct 4-mo periods when either 201TI or 99mTc-sestamibi were exclusively used for stress myocardial perfusion imaging. During the initial 4-mo period when 99mTc-sestamibi replaced 201TI, the mean whole-body film badge readings increased from 100 to 450 microSv/mo (p < 0.001) for nuclear med...

Com intuito de detectar a predição da resposta ao tratamento quimioterápico em carcinoma mama triplo negativo (CMTN), assim como, um padrão específico, propusemos cintilografia mamas com sestamibi-99mTc como método diagnóstico para avaliação. Foram estudadas 49 pacientes, no período 2011 2016, CMTN submetidas à pré-quimioterapia neoadjuvante e avaliação do espécime cirúrgico. Na foram avaliadas...

Introduction: Various radiopharmaceuticals, including 67Ga, 201Tl, and 99mTc-sestamibi have been used to differentiate benign from malignant thyroid nodules. 99mTc-Tetrofosmin, a lipophilic cationic radiotracer, and 99mTc-sestamibi have also been reported to accumulate in thyroid tumors. In this study, we evaluated the role of 99mTc-Tetrofosmin in the differentiation of malignant from ben...

BACKGROUND Scintigraphic myocardial perfusion imaging is the most widely used noninvasive modality for the detection of coronary artery disease (CAD). A technique for direct imaging of exercise-induced myocardial ischemia is highly desirable and preferable over perfusion imaging but is presently unavailable. We evaluated the feasibility and diagnostic accuracy of direct imaging of exercise-indu...

BACKGROUND Non-invasive cardiological methods have been used for the identification of myocardial damage in Chagas disease. OBJECTIVE To verify whether the rest/stress myocardial perfusion scintigraphy is able to identify early myocardial damage in the indeterminate form of Chagas disease. METHODS Eighteen patients with the indeterminate form of Chagas Disease and the same number of normal ...

BACKGROUND The manifestation of primary hyperparathyroidism with acute pancreatitis is a rare event. Ectopic paraesophageal parathyroid adenomas account for about 5%-10% of primary hyperparathyroidism and surgical resection results in cure of the disease. CASE PRESENTATION A 71-year-old woman was presented with acute pancreatitis and hypercalcaemia. During the investigation of hypercalcemia, ...

OBJECTIVES The proper nodal staging of non-small cell lung cancer is important for choosing the best treatment modality. Although computed tomography remains the first-line imaging test for the primary staging of lung cancer, its limitations for mediastinum nodal staging are well known. The aim of this study is to evaluate the accuracy of hybrid single-photon emission computed tomography and co...