Acquired hemophilia (AH) is an extremely rare condition in which autoantibodies (inhibitors) against clotting factor VIII induce acute and life-threatening hemorrhagic diathesis because of abnormal blood clotting. The mortality rate of AH is as high as 16%, and current treatment options are associated with adverse side effects. We investigated a therapeutic approach for AH called the modified B...

Acquired hemophilia (AH) is an extremely rare condition in which autoantibodies (inhibitors) against clotting factor VIII induce acute and life-threatening hemorrhagic diathesis because of abnormal blood clotting. The mortality rate of AH is as high as 16%, and current treatment options are associated with adverse side effects. We investigated a therapeutic approach for AH called the modified B...

OBJECTIVES To study the prevalence and associations of asteroid hyalosis (AH) in a series of autopsy eyes. METHODS Retrospective review of the University of California at Los Angeles (UCLA) autopsy eye database from 1965 to 2000 yielded 10,801 patients. The patients' medical histories were reviewed for evidence of diabetes mellitus, hypertension, hyperlipidemia, alcohol abuse, hypercalcemia, ...

The purpose of the study was to investigate prevalence of hostility, risk of arterial hypertension (AH), myocardial infarction (MI), and stroke, and genetic traits in open male population in Novosibirsk (Siberia, Russia). Random representative sample of 25–64-year-old men was examined in the WHO MONICAPsychosocial program in 1994. Hostility level was assessed by Cook-Medley test. Genotyping of ...

The GH dose-response effect of long-term continuous GH treatment on adult height (AH) was evaluated in 54 short children born small for gestational age (SGA) who were participating in a randomized, double-blind, dose-response trial. Patients were randomly and blindly assigned to treatment with either 3 IU (group A) or 6 IU (group B) GH/m(2).d ( approximately 0.033 or 0.067 mg/kg.d, respectively...

Abu Hamamid (AH) Neoproterozoic (Sm/Nd model age of 770 ± 20 Ma) mafic–ultramafic intrusion lies along a NE–SW fracture zone in the Shadli Metavolcanic Belt, south Eastern Desert, Egypt. AH intrusion is concentrically zoned with cumulate clinopyroxenebearing dunite core mantled by olivine clinopyroxenite, hornblende clinopyroxenite and hornblende gabbroic rim. The observed crystallization seque...

Background. Intraoperative team turnover is necessary given the duration of many cardiac surgical procedures, despite being an established risk factor for harm. We sought to determine if there was association between intraoperative anesthesia handoff (AH) and patient morbidity and/or mortality after surgery. Methods. All adult surgery procedures from November 2016 through 2021 were retrospectiv...

BACKGROUND AND PURPOSE The benefits of antihypertensive (AH) drugs on the risks of major cardiovascular outcomes have been demonstrated in clinical trials. However, approximately half of hypertensive patients do not adhere well to their prescribed AH therapy in actual practice. The purpose of this study was to assess the impact of adherence to AH agents on the incidence of cerebrovascular disea...

The Ah receptor is a presumed member of the superfamily of steroid/thyroid hormone receptors, a trace soluble protein present in a wide variety of vertebrate species that mediates the biological effects of halogenated aromatic hydrocarbons. In this paper, we report the purification to homogeneity of this protein (from the liver of C57BL/6J mice) and its N-terminal amino acid sequence. Selective...