www.thelancet.com Vol 390 July 22, 2017 341 More than three decades into the global HIV pandemic, there are still 2·1 million new infections each year and 36·7 million people are living with HIV. By mid2016, 18·2 million people were on antiretroviral treatment—about 50% of people living with HIV. Yet in 2015, 15 million people living with HIV were estimated to be unaware of their status and 1·1...

As cases of the novel coronavirus disease (COVID-19) continue to rise, so are concerns effects this pandemic could have on people living with HIV. In response pandemic, measures been put in place by African governments limit spread virus. We examine impact these ensuring progress towards HIV advocacy '90-90-90' 2020, i.e., 90% all will know their status, diagnosed receive sustained antiretrovir...

Skeletal muscle hormone-sensitive lipase (HSL) activity is increased by contractions and increases in blood epinephrine (EPI) concentrations and cyclic AMP activation of the adrenergic pathway during prolonged exercise. To determine the importance of hormonal stimulation of HSL activity during the onset of moderate- and high-intensity exercise, nine men [age 24.3 +/- 1.2 yr, 80.8 +/- 5.0 kg, pe...

conclusions the average value of the vancomycin mic for isolates from mrsa colonized patients was 2 µg/ml. trimethoprim /sulfamethoxazole was the second most effective anti-mrsa oral antibiotic in vitro. patients and methods from november 2009 to march 2011, a prospective study was performed in two emergency departments. patients at high risk for mrsa colonization were identified, and mrsa surv...

BACKGROUND Patients who die within 90 days of commencing renal replacement therapy (RRT) may be recorded by some centres and not others, and hence data on mortality and survival may not be comparable. However, it is essential to compare like with like when analysing differences between modalities, centres and registries. It was decided, therefore, to look at the incidence of deaths within 90 da...

RATIONALE Obstructive sleep apnea (OSA) has been associated with increased cancer mortality, but whether it is also associated with cancer incidence is unknown. OBJECTIVES To investigate whether OSA is associated with increased cancer incidence in a large clinical cohort. METHODS A multicenter, clinical cohort study including consecutive patients investigated for suspected OSA between 2003 ...

One third of cases of cerebral ischemia have no clear etiology. A humoral response to the atherosclerotic plaques components beta2-glycoprotein l (beta2-gpl) and heat-shock proteins (Hsp) might be involved in the pathogenesis of stroke. This case-control study includes a complete profile of anti-beta2-gpl antibodies and testing of IgG antibodies to the 60/65 kilodaltons (kDa) Hsp in stroke pati...