INTRODUCTION Single nucleotide polymorphisms within promoter or other regulatory sequences of cytokine genes mainly influence the level of production and secretion of proteins. A large amount of evidence has shown that cytokine gene variations alter graft survival length after kidney transplantation. We studied the association of gene polymorphisms in the interlekin-10 gene (IL10; -1082 G/A), i...

N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N1-(2-fluoro-5-methyl phenyl)-urea (ABT-869) is a novel multitargeted receptor tyrosine kinase inhibitor that demonstrates single-agent activity in preclinical studies and has undergone phase I and II clinical trials. We characterized the mechanism of action of ABT-869 by examining vascular changes after treatment (25 mg/kg per day) in HT1080 fibrosarcoma a...

Acute rejection (AR) recurrence after liver transplantation (LT) is one of the major complications that leads to chronic graft dysfunction. It has been reported that the polymorphisms in some cytokine genes are associated with human liver allograft rejection. This study mainly investigated the associations between polymorphisms in the genes encoding interleukin-10 (IL10), transforming growth fa...

[1] Atmospheric correction for the ocean color products derived from the Moderate Resolution Imaging Spectroradiometer (MODIS) uses two near-infrared (NIR) bands centered at 748 and 869 nm. Ocean is usually assumed to be black at these two NIR wavelengths. For Case-2 and high productive Case-1 waters, however, ocean could have significant contributions in the NIR, leading to significant under-e...

Transcriptome profiling via cDNA microarray analysis identified 869 genes that are differentially expressed in developing tomato (Solanum lycopersicum) pericarp. Parallel phenotypic and targeted metabolite comparisons were employed to inform the expression analysis. Transcript accumulation in tomato fruit was observed to be extensively coordinated and often completely dependent on ethylene. Mut...

INTRODUCTION: Transforming growth factor-beta 1 (TGFβ1) is a potent suppressive cytokine that contributes to chronic hepatitis B (CHB) infection. Disparities in TGFβ1 production among individuals have been attributed to TGFβ1 genetic polymorphisms. We examined whether three putative polymorphisms in TGFβ1[-509 C/T (rs1800469), +869 C/T (rs1800470), and +11929 C/T (rs1800472)]are associated wit...

We give a definition of character sheaves on the group compactification which is equivalent to Lusztig’s definition in [Moscow Math. J. 4 (2004) 869-896]. We also prove some properties of the character sheaves on the group compactification.

Correction for ‘Characterizing surface wetting and interfacial properties using enhanced sampling (SWIPES)’ by Hao Jiang et al., Soft Matter, 2019, 15, 860–869, DOI: 10.1039/C8SM02317D.

Soon after they were developed, very-large-scale integration circuits became an important part of the forefront of computing. The development of reliable interconnect directly on silicon wafers enabled circuits consisting of many devices to be built very easily. As the design space exploded in size with the flexibility of VLSI, an important question arose: is there any way to provide a good low...

INTRODUCTION ......................................................................................854 I. THEORIES AND CRITIQUES OF PUNITIVE DAMAGES ........................857 A. The History and Theories of Punitive Damages Awards ......... 857 B. Critiques of Punitive Damages ........................................... 860 II. THE SUPREME COURT’S PUNITIVE DAMAGES JURISPRUDENCE .......863 III....