نتایج جستجو برای: 705 and 79

تعداد نتایج: 16836613  

Journal: :Plastic and Reconstructive Surgery - Global Open 2020

Journal: :JAPAN TAPPI JOURNAL 1980

Journal: :The American Journal of the Medical Sciences 1845

2014
Amy L. Caroline Diana S. Powell Laura M. Bethel Tim D. Oury Douglas S. Reed Amy L. Hartman

BACKGROUND Development of antiviral drugs that have broad-spectrum activity against a number of viral infections would be of significant benefit. Due to the evolution of resistance to currently licensed antiviral drugs, development of novel anti-influenza drugs is in progress, including Favipiravir (T-705), which is currently in human clinical trials. T-705 displays broad-spectrum in vitro acti...

Journal: :The Journal of Automatic Chemistry 1984
C. Ferré M. J. Castiñeiras M. J. Alsina R. Galimany J. Riera

Journal: :Astronomy & Astrophysics 2005

Journal: :American Journal of Obstetrics and Gynecology 2020

2016
Bindumadhav M. Marathe Sook-San Wong Peter Vogel Fernando Garcia-Alcalde Robert G. Webster Richard J. Webby Isabel Najera Elena A. Govorkova

Current anti-influenza therapy depends on administering drugs soon after infection, which is often impractical. We assessed whether combinations of oseltamivir (a neuraminidase inhibitor) and T-705 (a nonspecific inhibitor of viral polymerases) could extend the window for treating lethal infection with highly pathogenic A(H5N1) influenza virus in mice. Combination therapy protected 100% of mice...

2017
Siva Balakrishnan

It is worth keeping in mind the trade-off: Bayes estimators although easy to compute are somewhat subjective (in that they depend strongly on the prior π). Minimax estimators although more challenging to compute are not subjective, but do have the drawback that they are protecting against the worst-case which might lead to pessimistic conclusions, i.e. the minimax risk might be much higher than...

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