نتایج جستجو برای: 68ga dotanoc petct

تعداد نتایج: 1545  

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013
Punit Sharma Alok Thakar Sudhir Suman K C Varun Singh Dhull Harmandeep Singh Niraj Naswa Rama Mohan Reddy Sellam Karunanithi Rajeev Kumar Rakesh Kumar Arun Malhotra Chandrasekhar Bal

UNLABELLED The purpose of this study was to evaluate the role of (68)Ga-labeled DOTANOC PET/CT for baseline evaluation of patients with head and neck paragangliomas (HNPs). METHODS The data for 26 patients (mean age ± SD, 34.3 ± 10.4 y; 50% men) with known or suspected HNPs who underwent (68)Ga-DOTANOC PET/CT for staging were retrospectively analyzed. PET/CT was performed after intravenous in...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010
Valentina Ambrosini Davide Campana Lisa Bodei Cristina Nanni Paolo Castellucci Vincenzo Allegri Gian Carlo Montini Paola Tomassetti Giovanni Paganelli Stefano Fanti

UNLABELLED Several authors reported the superiority of (68)Ga-DOTANOC PET/CT to conventional imaging (CI) for the assessment of neuroendocrine tumors (NET). However, the detection of a higher number of lesions is not necessarily followed by a modification of disease stage or therapeutic approach. The aim of this study was to assess the impact of (68)Ga-DOTANOC PET/CT on the clinical management ...

2014
Punit Sharma Varun Singh Dhull Chandrasekhar Bal Arun Malhotra Rakesh Kumar

Von Hippel-Lindau (VHL) syndrome is a rare neoplastic disorder characterized by central nervous system (CNS) and visceral tumors. We here present (68)Ga-labelled [1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid]-1-Nal3-Octreotide positron emission tomography computed tomography findings in a 52 year old female with VHL syndrome, demonstrating both CNS and visceral tumors.

2016

At that time, five years after initial diagnosis, the patient first presented at our endocrine department for further treatment. 68Ga-DOTANOC-PET/CT revealed progressive, systemic disease with hepatic, lymphatic, and pulmonal metastases, without relevant tracer uptake. The patient was not willing to undergo systemic chemotherapy. We therefore discussed an off-label use of everolimus 10mg daily ...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2015
Valentina Ambrosini Davide Campana Giulia Polverari Chiara Peterle Stefania Diodato Claudio Ricci Vincenzo Allegri Riccardo Casadei Paola Tomassetti Stefano Fanti

UNLABELLED This study was performed to investigate the role of (68)Ga-DOTANOC SUVmax as a potential prognostic factor in patients with pancreatic neuroendocrine tumor (pNET). METHODS Among the patients who underwent (68)Ga-DOTANOC PET/CT, we retrospectively collected the data of those who had G1 or G2 pNET (2010 World Health Organization classification), presented with disease on PET/CT and C...

2017
Eleni Gourni Luigi Del Pozzo Mark Bartholomä Yvonne Kiefer Philipp T. Meyer Helmut R. Maecke Jason P. Holland

Radiotracers incorporating the urea-based Glu-NH-C(O)-NH-Lys group have gained prominence due to their role in targeting prostate-specific membrane antigen (PSMA)-a clinical biomarker of prostate cancer. Here, the synthesis, radiolabeling, and in vitro and in vivo characterization of two 68Ga-radiolabeled Glu-NH-C(O)-NH-Lys radiotracers conjugated to the desferrioxamine B (DFO) chelate were eva...

2017
Ioannis Ilias Georgios Meristoudis

Few reports have presented data and results on functional (i.e., nuclear medicine) imaging of paragangliomas and pheochromocytomas (PGLs/PHEOs) for von Hippel-Lindau (VHL) patients. Nuclear medicine localization modalities for chromaffin tumors can be specific or nonspecific. Specific methods make use of the expression of the human norepinephrine transporter (hNET) and vesicular monoamine trans...

2013
Frank Rösch

68Ga faces a renaissance initiated by the development of new 68Ge/68Ga radionuclide generators, sophisticated 68Ga radiopharmaceuticals, preclinical research and state-of-the-art clincial diagnoses via positron emission tomography/computed tomography (PET/CT). A new type of 68Ge/68Ga generator became commercially available in the first years of the 21st century, with eluates based on hydrochlor...

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