INTRODUCTION Early localisation of disease recurrence after definitive treatment of prostate cancer is vital to determine suitability for salvage treatment. Our aim was to further investigate the relationship between prostate specific antigen (PSA) level and detection of suspected cancer recurrence using 68  Ga-PSMA PET/CT in patients with biochemical recurrence after radical prostatectomy (RP)...

PURPOSE The prostate-specific membrane antigen (PSMA) was shown to be overexpressed on the neovasculature of several malignancies. Here, the role of Ga-HBED-CC-PSMA PET/CT for the detection of PSMA expression in patients with metastasized differentiated thyroid cancer (DTC) was evaluated. METHODS Six patients with iodine-negative and F-FDG-positive metastasized DTC (mean TG, 1616 ng/mL) recei...

Abstract Background Consensus statements was published by EAU and EANM to clarify some uncertainties on PSMA PET/CT response assessment in 2020. We aimed investigate the criteria for according comparing with serum PSA changes determine factors affecting therapy evaluation. Results A high concordance found between [ 68 Ga]Ga-PSMA-11 responses 0.84 of Gamma coefficient obtained. Between concordan...

Despite the progress in diagnosis and treatment, prostate cancer (PCa) is one of the main causes for cancer-associated deaths among men. Recently, prostate-specific membrane antigen (PSMA) binding tracers have revolutionized the molecular imaging of this disease. The translation of these tracers into therapeutic applications is challenging because of high PSMA-associated kidney uptake. While bo...

Purpose of the study: to present current data regarding challenges in treatment castration-resistant prostate cancer (CRPC) and relationship between CRPC expression prostate-specific membrane antigen (psma). Material Methods. The search for relevant sources was carried out Pubmed, elibrary, Medline databases. review included 43 publications, most which were published over past 5 years. Results....