aquatic and atmospheric environments. Other highly topical issues are the evolutions of toxins, secretion systems, and antibiotic resistance. In the third section, the 4 chapters extensively discuss the evolution of selected groups of microbial pathogens: group A Streptococcus and Staphylococcus aureus; enteric pathogens such as Escherichia coli, Salmonella enterica, and Yersinia spp.; Mycobact...

Introduction In the second half of the 1970s, Lloyd J. Old and his group at Memorial Sloan-Kettering Cancer Center (MSKCC) discovered the first human cancer antigens by establishing an approach called “autologous typing.” The key preconditions of these discoveries were improvements in establishing human cancer cell lines from fresh tissue specimens and cultures from autologous healthy tissues, ...