*Correspondence: 9 Department of Biochemistry and Biomedical Sciences, Health Sciences Centre, Room 10 4H24, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N3Z5, 11 Canada. Phone: 1-905-525-9140 Ext 22703 Fax: 1-905-522-9033. 12 e-mail: [email protected] 13 14 Running Title: DegP: A Structure Driven Functional Model 15

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Short Data Record Adaptive Filtering: The Auxiliary-Vector Algorithm 1 George N. Karystinos,∗ Haoli Qian,∗ Michael J. Medley,† and Stella N. Batalama∗ ∗Department of Electrical Engineering, State University of New York at Buffalo, 332 Bonner Hall, Buffalo, New York 14260; and †Air Force Research Laboratory, IFGC, 525 Brook Road, Rome, New York 13441 E-mail: [email protected], [email protected]...

Klaus Flechsenhar1 and Timothy McAlindon2 1Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, Germany 2Tufts Medical Center, Chief, Division of Rheumatology, Boston, USA *Corresponding author: Klaus Flechsenhar, MD, Sanofi-Aventis Deutschland GmbH, Therapeutic Area Immunology, Cytokine Modulation, Industriepark Hoechst, Building H821, Room 525, D-65926 Frankfurt am Main Germany, Tel: +49 69 30...

The transfer of triplet excitation from chlorophyll to zeaxanthin in liposom es is a function o f temperature and pigment concentration. At 525 nm both chlorophyll and zeaxanthin triplet states are observed. The result is a biphasic increase in absorption. The rise time o f absorption by the chlorophyll triplet is much faster, than by the zeaxanthin triplet. With increasing temperature the cont...

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BACKGROUND microRNAs (miRNAs) are non-coding RNAs that alter the stability and translation efficiency of messenger RNAs. Ionizing radiation (IR) induces rapid and selective changes in miRNA expression. Depletion of the miRNA processing enzymes Dicer or Ago2 reduces the capacity of cells to survive radiation exposure. Elucidation of critical radiation-regulated miRNAs and their target proteins o...

The understanding of molecular mechanism underlying ischemia/reperfusion-induced neuronal death and neurological dysfunction may provide therapeutic targets for ischemic stroke. In this study, miR-525-5p is clearly reduced in the ischemic brain after oxygen-glucose deprivation (OGD). Using TargetScan, MicroCosm Targets version 5, and microRNA.org databases, we identified miR-525-5p as a possibl...

Uniform thin films of a metal-organic framework, which is constructed from free-base porphyrin linkers and hexa-zirconium nodes (MOF-525), are solvothermally grown on conducting substrates. Subsequently, solvothermal post metalations are employed to prepare the Zn-MOF-525 and Co-MOF-525 thin films. All the thin films are electroactive in aqueous media.

A newly developed phenoxyalkylamine derivative, 2-isopropyl-5-[3-(2-methoxyphenoxy)propylamino]-2-(3,4, 5-trimethoxyphenyl)-valeronitrile fumarate (HV-525), was investigated in intact dogs and in isolated dog atria perfused with anesthetized donor dog's arterial blood. When 0.3 mg/kg of HV-525 was intravenously administered to the donor dog, a depressor effect without significant changes in hea...