4D ultrasound imaging of the fetal heart relies on reconstructions from B-mode images. In the presence of fetal or mother’s motion, current approaches suffer from artifacts. We propose to use many sweeps and exploit the resulting redundancy to recover from motion by reconstructing a 4D image which is consistent in phase, space and time. We first quantified the performance of 7 formulations on s...

German Cancer Research Center (DKFZ), Heidelberg, Germany We propose a new method for PET/MR respiratory motion compensation, which is based on strongly undersampled measured MR data and a) runs in parallel with the PET acquisition, b) can be interlaced with clinical MR sequences, and c) can be acquired with measurement times as short as 0.5 min per bed position. An MR dataset covering the free...

We present an imaging and image reconstruction pipeline that captures the dynamic three-dimensional beating motion of the live embryonic zebrafish heart at subcellular resolution. Live, intact zebrafish embryos were imaged using 2-photon light sheet microscopy, which offers deep and fast imaging at 70 frames per second, and the individual optical sections were assembled into a full 4D reconstru...

Real-time three-dimensional (also known as 4D) ultrasound imaging using matrix array probes has the potential to create large-volume information of entire organs such as the liver without external tracking hardware. This information can in turn be placed into the context of a CT or MRI scan of the same patient. However for such an approach many image processing challenges need to be overcome an...

We have worked on the measurement protocol and related image reconstruction of 4D data sets in the field of time-resolved Contrast-Enhanced Magnetic Resonance Angiography (CE-MRA). The method aims at improving the interpolation of sparsely sampled -space data. It is based on exploiting prior knowledge on the time courses (TCs) of the image pixels, when monitoring the uptake of contrast agents i...

PURPOSE Respiratory organ motion is still the major challenge of various image-guided treatments in the abdomen. Dynamic organ motion tracking, necessary for the treatment control, can be performed with volumetric time-resolved MRI that sequentially acquires one image and one navigator slice. Here, a novel imaging method is proposed for truly simultaneous high temporal resolution acquisition. ...

INTRODUCTION 4D cardiovascular MRI applications typically require prolonged scan times and suffer from artifacts due to physiological motion. Compressed sensing (CS) and its combination with parallel imaging (PI) have recently emerged as valuable tools for accelerating MRI acquisitions by reconstructing images from undersampled k-space data. The required incoherent artifact in CS is usually ach...

in this paper, we review novel techniques in the emerging field of spatiotemporal 4d pet imaging. we will discuss existing limitations in conventional dynamic pet imaging which involves independent reconstruction of dynamic pet datasets. various approaches that seek to attempt some or all of these limitations are reviewed in this work, including techniques that utilize iterative temporal smooth...

Nuclear cardiac imaging is a noninvasive, sensitive method providing information on cardiac structure and physiology. Single photon emission tomography (SPECT) evaluates myocardial perfusion, viability, and function and is widely used in clinical routine. The quality of the tomographic image is a key for accurate diagnosis. Image filtering, a mathematical processing, compensates for loss of det...

BACKGROUND Four-dimensional (4D) ultrasound scanning (3D real-time mode) can improve the orientation of the anatomy of the area of interest and navigation by controlling the needle position. The objectives of this study were to identify the optimal technique for navigation and to assess clinically the efficacy of 4D ultrasound navigation for epidural anaesthesia at lower thoracic and lumbar lev...