Background and aim: Colon cancer is the third most prevalent cancer in Iran. Prolonged colon inflammation is an important factor, in the development of colon cancer. Ginger has anti-inflammatory properties due to its content of [6]-gingerol and hence can play a role in the prevention of colon cancer. In this research the effects of ginger extract on reducing expression of the C...

background: clinical and epidemiological variation was seen between the colon cancer (cc) and rectum cancer (rc). so, there is not so much data available about the epidemiological and clinicopathological differences and prognostic factors regarding to cc and cr in iran, we aimed to perform this study. methods: all cases of cc and rc referred to oncology and gastroenterology wards of taleghani g...

BACKGROUND MicroRNAs are a class of new noncoding RNA that play important roles in the pathogenesis of tumor. Rs3746444 in miR-499 is suggested to be associated with cancer susceptibility. In the present study, we assess the association between miR-499 rs3746444 polymorphism and cancer susceptibility through a meta-analysis. METHODS We searched relevant articles from the PubMed and Embase dat...

Objective(s): Determination of stages of colon cancer is done by biopsy usually after surgery. Metabolomics is the study of all the metabolites using LC-MS and 1HNMR spectroscopy with chemometric techniques. The stages of colon cancer were detected from patients' sera using 1HNMR. Materials and Methods: Five ml blood was collected from 16 confirmed patients referred for colonoscopy.  One group ...

background: solid tumors may occur in 3% of the patients with chronic myeloid leukemia (cml). in this paper, we presented a case of cml following treatment of colon cancer. case presentation: a 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...

conclusions we have found significant associations between lifestyle factors (alcohol consumption and smoking) and mental health problems (depression and insomnia) and crc screening uptake. to improve overall crc screening uptake in the us, it is important to consider racial differences in predictors and tailor appropriate interventions to each racial/ethnic group. background mortality from col...

a 78-year-old woman with a history of colon cancer with metastasis to the liver was presented to our emergency department because of bilateral groin pain and difficulty in walking, which had gradually increased during the previous 5 days. the pain was of sudden onset, radiating to the back, without aggravating or relieving factors. it was associated with constipation, dysuria and vaginal discha...

BACKGROUND Owing to inconsistent and inconclusive results, we performed a meta-analysis to derive a more precise estimation of the association between miR-499 rs3746444 polymorphism and cancer risk. METHODOLOGY/PRINCIPAL FINDINGS A systematic search of the Pubmed, Excerpta Medica Database (Embase) and Chinese Biomedical Literature Database (CBM) databases was performed with the last search up...

in western countries there is a growing incidence in obesity, inflammatory bowel disease (ibd) and colorectal cancer (crc), which places an increasingly important burden on the health care system. in the current decade, changes in intestinal microflora (i.e., dysbiosis) are likely the result of environment factors such as food, lifestyle, and medications which have been shown in obesity and ibd...

conclusions due to the significant reduction in the mean inactivation dose of colon cancer cells in the presence of gold nanoparticles, it seems that gnps are suitable options to achieve a new approach in order to improve radiotherapy efficiency without increasing the prescribed radiation dose. results cell survival in the presence of gnps was more than 90% and the maximum uptake of gnps was ob...