نتایج جستجو برای: 4672
تعداد نتایج: 56 فیلتر نتایج به سال:
background: knowledge production and evaluation are two important functions of health research system (hrs). in this article, we aimed to reveal the correlation between evaluation of health research organizations and health knowledge production promotion. methods: a comprehensive evaluation system was developed to evaluate the academic performance of national medical science universities on an ...
Purpose: Individually targeting B-cell antigens with monoclonal antibody therapeutics has improved the treatment of non-Hodgkin lymphoma (NHL). We examined if the antitumor activity of rituximab, CD20-specific antibody, could be improved by simultaneously targeting CD40 with the humanized monoclonal antibody dacetuzumab (SGN-40). Experimental Design: Dacetuzumab was dosed with rituximab to dete...
BACKGROUND Acute kidney injury (AKI) is common after cardiac surgery, and expeditious recognition with specific biomarkers may help improve outcome. OBJECTIVE Because the economic impact of a biomarker-based diagnostic strategy is unknown, we assessed the cost-effectiveness of using urinary neutrophil gelatinase-associated lipocalin (NGAL) for the diagnosis of AKI after cardiac surgery compar...
A previously isolated exoelectrogenic bacterium, strain SD-1(T), was further characterized and identified as a representative of a novel species of the genus Geobacter. Strain SD-1(T) was Gram-negative, aerotolerant, anaerobic, non-spore-forming, non-fermentative and non-motile. Cells were short, curved rods (0.8-1.3 µm long and 0.3 µm in diameter). Growth of strain SD-1(T) was observed at 15-4...
OBJECTIVES The overall objective of this study was to estimate the costs and outcomes associated with treatment with valsartan for post-myocardial infarction (post-MI) patients with left ventricular systolic dysfunction, heart failure, or both, who are not suitable for treatment with angiotensin-converting enzyme (ACE) inhibitors, compared to placebo. METHODS A Markov model, using data drawn ...
Abstract Background Lutein and zeaxanthin are antioxidant anti-inflammatory carotenoids derived from foods such as fruit vegetables. Serum concentrations of (Ls) Zeaxanthin (Zs) reflect habitual dietary intake. This study examined the cross-sectional longitudinal relationships between Ls Zs frailty, probable sarcopenia, indices physical function in TILDA. Methods The analysis included n=4672 co...
INTRODUCTION The aim of this prospective, observational, multicenter study was to examine the epidemiology and management costs of bone metastatic disease (BMD) in patients with lung cancer. METHODS The analysis included all patients with BMD from lung cancer diagnosed between May 2006 and May 2007 in 40 centers. We analyzed their management and the direct costs of BMD from the health care pr...
OBJECTIVE Non-communicable diseases (NCDs) are the biggest cause of death in Europe putting an unsustainable burden on already struggling health systems. Increases in obesity are a major cause of NCDs. This paper projects the future burden of coronary heart disease (CHD), stroke, type 2 diabetes and seven cancers by 2030 in 53 WHO European Region countries based on current and past body mass in...
Little is known about the optimal duration of therapy with an anti-tumor necrosis factor (TNF) agent and/or an immunomodulator for patients with inflammatory bowel disease (IBD). We performed a systematic search of the literature to identify studies reporting after de-escalation (drug cessation or dose reduction) of anti-TNF agents and/or immunomodulators in patients in remission from IBD. Stud...
OBJECTIVE To investigate the association between maternal pregnancy intention and professional antenatal and delivery care utilization. METHODS Our data were derived from the 2011 nationally representative Bangladesh Demographic Health Survey. We included antenatal and delivery care utilization data of the most recent live births for women for the previous three years (n = 4672). We used mult...
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