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Cholera vaccines developed by the deletion of CTX genes from Vibrio cholerae induce a residual reactogenicity in up to 10% of vaccinees. A novel cytotonic agent named secreted CHO cell elongating protein (S-CEP) was purified from culture supernatants of CVD 103-HgR (Levine et al., Lancet ii:467-470, 1988). Five fractionation steps yielded electrophoretically pure S-CEP with an M(r) of 79,000. A...

[*] Prof. C. A. Mirkin, J.-H. Lim, D. S. Ginger, K.-B. Lee, J. Heo, J.-M. Nam Department of Chemistry and Institute for Nanotechnology Northwestern University 2145 Sheridan Road, Evanston, IL 60208-3113 (USA) Fax: (+1)847-467-5123 E-mail: [email protected] [**] C.A.M. acknowledges the AFOSR, DARPA, and NSF for support of this research. D.S.G. thanks the NIH for an NRSA Postdoctoral...

PepV, a dipeptidase found in culture fluids of Streptococcus gordonii FSS2, was purified and characterized, and its gene was cloned. PepV is a monomeric metalloenzyme of approximately 55 kDa that preferentially degrades hydrophobic dipeptides. The gene encodes a polypeptide of 467 amino acids, with a theoretical molecular mass of 51,114 Da and a calculated pI of 4.8. The S. gordonii PepV gene i...

Skogsbergiella tetrathrix sp. nov. and S. species A, species of the family Cylindroleberididae are described from the Drake Passage (59°21.97´S - 60°4.27´W to 59°22.55´S - 60°4.01´W, depth 2372-2380 m) and Weddell Sea  (75°49.9´S-27°31.7´W to 74°51.55´S-27°40.3´W, depth 467-475m) respectively. Skogsbergiella tetrathrix sp.nov. is very close to S. macrothrix Kornicker, 1975 but differs by greate...

CAP value among the 3 groups. MANOVA multivariate analysis evaluated differences in overall CAPs and the effects of age, gender, Mueller grade and stings number. A P , 0.05 was considered statistically significant. Data were analysed by ‘SPSS’ 13.0 (SPSS Inc., Chicago, IL). We called NS patients to check if they were stung after VIT discontinuation. Results: We selected 84 NS, 72 SP3 and 76 SP5...