Abstract Background and Aims Vascular calcification (VC) represents a common pathological feature of cardiovascular disease VC caused by hyperphosphatemia is one the hallmarks chronic kidney (CKD). Therefore, elucidating pathogenesis may have significant clinical benefits for CKD patients. smooth muscle cells challenged with high-phosphate (Pi) actively participate to trans-differentiating into...

BACKGROUND AND PURPOSE Restriction spectrum imaging is a sensitive DWI technique for probing separable water diffusion compartments in tissues. Here, we evaluate RSI-CMs derived from the spherically-restricted water compartment for improved tumor conspicuity and delineation from nontumor tissue and reduced sensitivity to edema compared with high-b-value DWI and ADC. MATERIALS AND METHODS RSI ...

Semi-hardwood cuttings of ‘Frantoio’ (high rooting ability) and ‘Gentile di Larino’ (low rooting ability) cultivars were obtained from 1-year-old olive shoots sampled in mid-August during the 2000 and 2001 growing season. Semi-hardwood cuttings were dipped in IBA 4000 ppm and H2O2 (0%-control or 3.5% w/v) solutions before rooting in greenhouse equipped with an automatic mist system. At 57 and 8...

The present study was to synthesize a novel multi-targeted kinase inhibitor and evaluated its anticancer effects on a hepatocellular carcinoma xenograft model. In our study, in vivo efficacy was determined in nude mice bearing HuH7 human HCC xenografts. The mice were randomly divided into the following five groups with the use of a randomization chart (n = 8 in each group): high-dose BZG-4000 g...