A series of derivatives (E)-6-chloro-5-fluoro-2-styryl-1H-benzo[d]imidazole, and 5-fluoro-2-methylN-phenyl-1H-benzo[d]imidazol-6-amine was synthesized. Compounds confirmed by melting point, FT-IR, 1HNMR, Mass spectral analytical techniques predicted for their ADME, Pharmacokinetic properties.Synthesized compounds screened better antibacterial antiinflammatory activity. To synthesize a novel tri...

The molecular distribution of the cyanine dye (5-chloro-2-[3-[5-chloro-3-(4-sulfobutyl)-2(3H)benzothiazolylidine]-1-propenyl]-3-(4-sulfobutyl)-benzothiazolium hydroxide triethylamine salt, NK-3796) in aqueous solution was investigated using absorption and emission spectroscopy. Dimers of the dye are formed in concentrated solutions, while monomers dominate more diluted solutions. J aggregates a...

The asymmetric unit of the title compound, {[HgLCl2]·0.5CHCl3} n (L = N-(pyridin-4-ylmeth-yl)pyridin-3-amine, C11H11N3), contains one HgII ion, one bridging L ligand, two chloride ligands and a chloro-form solvent mol-ecule with half-occupancy that is disordered about a crystallographic twofold rotation axis. Each HgII ion is coordinated by two pyridine N atoms from two symmetry-related L ligan...

The asymmetric unit of the title salt, (C(6)H(14)N)(3)[FeCl(4)]Cl(2), consists of a tetra-hedral tetra-chloro-ferrate anion, three independent 2-methyl-piperidinium cations and two chloride ions. All the piperidine rings adopt chair conformations. In the crystal, the organic cations and the free chloride anions are linked into chains parallel to the a axis by N-H⋯Cl hydrogen bonds.

A series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (C1-C7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. All the synthesis compounds have been characterized by 1HNMR, IR and Mass spectral data. The compounds were purified...

The β-blocker (S)-esmolol, has been synthesized in 97% enantiomeric excess and 26% total yield a four-step synthesis, with transesterification step of the racemic chlorohydrin methyl 3-(4-(3-chloro-2-hydroxypropoxy)phenyl)propanoate, catalysed by lipase B from Candida antarctica Syncozymes, Shanghai, China. (S)-penbutolol, 99% 22% yield. 1-chloro-3-(2-cyclopentylphenoxy)propan-2-ol was catalyze...

The aerobic cometabolism of chlorobenzoic acids (CBAs) by Rhodococcus sp. R04 was accomplished by augmenting the medium with organic carbon sources. In mineral medium supplemented with glucose (MMG), 0.5 mM 2-CBA was incompletely metabolized after the 5day incubation, while the near-complete disappearance of 0.5 mM 4-CBA was monitored. Over the 5-day incubation period, the concentration of chlo...