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The bile salt export pump (BSEP, ABCB11) is predominantly responsible for the efflux of bile salts, and disruption of BSEP function is often associated with altered hepatic homeostasis of bile acids and cholestatic liver injury. Accumulating evidence suggests that many drugs can cause cholestasis through interaction with hepatic transporters. To date, a relatively strong association between dru...
The double stranded small active RNA (saRNA)- p21-saRNA-322 inhibits tumor growth by stimulating the p21 gene expression. We focused our research of p21-saRNA-322 on colorectal cancer because 1) p21 down-regulation is a signature abnormality of the cancer, and 2) colorectal cancer might be a suitable target for in situ p21-saRNA-322 delivery. The goal of the present study is to learn the activi...
2.1. Definitions: groups, subgroups, homomorphisms. (1) Which of the following are groups? If yes, prove the group axioms. If not, show that an axiom fails. (a) The “half integers” 12Z = { a 2 | a ∈ Z } ⊂ Q, under addition. (b) The “dyadic integers” Z[ 12 ] = { a 2k | a ∈ Z, k ≥ 0 } ⊂ Q, under addition. (c) The non-zero dyadic integers, under multiplication. (2) [DF1.1.9] Let F = { a+ b √ 2 | a...
Cross-section data on secondary level student choices provide evidence on factors influencing the decision to study economics. Such evidence makes a key contribution to the broader debates on why student numbers have been falling in economics and why women are reluctant economists. Greater mathematical aptitude and prior knowledge of the subject influence the decision to study economics, and a ...
http://bmj.com/cgi/content/full/322/7278/98 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/322/7278/98/DC1 "extra references" References http://bmj.com/cgi/content/full/322/7278/98#otherarticles 11 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/322/7278/98#BIBL This article cites 15 art...
http://bmj.com/cgi/content/full/322/7288/724 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/322/7288/724#otherarticles 21 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/322/7288/724#BIBL This article cites 7 articles, 3 of which can be accessed free at: Rapid responses http://bmj.com/cgi/ele...
http://bmj.com/cgi/content/full/322/7286/599 Updated information and services can be found at: These include: Data supplement http://bmj.com/cgi/content/full/322/7286/599/DC1 "Details of literature search" References http://bmj.com/cgi/content/full/322/7286/599#otherarticles 5 online articles that cite this article can be accessed at: http://bmj.com/cgi/content/full/322/7286/599#BIBL This artic...
http://bmj.com/cgi/content/full/322/7291/912 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/322/7291/912#otherarticles 5 online articles that cite this article can be accessed at: Rapid responses http://bmj.com/cgi/eletter-submit/322/7291/912 You can respond to this article at: http://bmj.com/cgi/content/full/322/7291/912#responses fr...
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