From the invasive Citrobacter freundii strain 3009, an invasion determinant was cloned, sequenced, and expressed. Sequence analysis of the determinant showed high homology with the fim determinant from Salmonella enterica serovar Typhimurium. The genes of the invasion determinant directed invasion of recombinant Escherichia coli K-12 strains into human epithelial cell lines of the bladder and g...

The mechanism by which the embryonic vasculature forms can be divided into two major processes: vasculogenesis and angiogenesis. In vasculogenesis, mesodermally derived endothelial cell precursors or angioblasts migrate to future vessel sites and coalesce with neighbors to form endothelial cell cords, which lumenize and become ensheathed by supporting smooth muscle cells or pericytes. This prim...

2-Oxoglutarate dehydrogenase (lipoamide) (( OGDH: 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating), EC 1.2.4.2 )) is a component enzyme of the 2-oxoglutarate dehydrogenase complex. We have cloned a human cDNA encoding OGDH from a fetal liver cDNA library by plaque hybridization with a mixture of oligonucleotide probes designed from the amino acid sequences ...

There is a growing body of evidence in support of sleep-dependent memory consolidation and plasticity. However, there are also examples of memory development and plasticity in the absence of sleep, casting doubt on an exclusive sleep-dependent memory hypothesis. As CMLS, Cell. Mol. Life Sci. 61 (2004) 3009–3015 1420-682X/04/243009-07 DOI 10.1007/s00018-004-4351-1 © Birkhäuser Verlag, Basel, 200...