Emerging data suggest that measurement of serum IgE to peanut components can be clinically helpful and more accurate than IgE to whole peanut to predict peanut allergy. Not all studies have used prospective samples, multiple components and oral challenges. Currently, there are no data on this topic involving Italian children. 32 patients (23 males; median age 9 years) with reported history for ...

Anaphylaxis caused by allergen sensitization and vaccination is a serious health concern. The severity of anaphylaxis associated with the presence immunoglobulin E (IgE) antibodies that bind to allergens high affinity. Here, we report development unique Interleukin-13 (IL-13)-producing follicular helper T (TFH) cell subset, designated TFH2 cells, which tightly production high-affinity IgE antib...

Cross-linking FcepsilonRI on mast cells by immunoglobulin E (IgE) and antigen (Ag) initiates cascades leading to antiparasitic or allergic responses. It was recently reported that IgE without antigen, IgE(-Ag), actively promotes mast cell survival. Although we have demonstrated that the immunoreceptor tyrosine-based activation motif within FcRgamma is essential for IgE(-Ag)-induced mast cell su...

In order to determine the normal values of total IgE in children, 3270 sera were taken from 0-14 year old males and females in different parts of Tehran, the capital of Iran. The technique which was used to measure total IgE was ELISA method using monoclonal anti-IgE antibody. The results of this research indicated that the lower value for IgE was detected in children at birth (X=3.S3 IU/m...

BACKGROUND Peanut may cause severe reactions in allergic individuals. The objective was to evaluate IgE antibodies to various recombinant (r) peanut and birch pollen allergens in relation to IgE levels to whole peanut extract and severe allergic reactions to peanut. METHODS Seventy-four Swedish peanut-allergic patients (age: 14-61 years) reported previous peanut exposure and associated sympto...

emerging data suggest that measurement of serum ige to peanut components can be clinically helpful and more accurate than ige to whole peanut to predict peanut allergy. not all studies have used prospective samples, multiple components and oral challenges. currently, there are no data on this topic involving italian children. 32 patients (23 males; median age 9 years) with reported history for ...

in order to determine the normal values of total ige in children, 3270 sera were taken from 0-14 year old males and females in different parts of tehran, the capital of iran. the technique which was used to measure total ige was elisa method using monoclonal anti-ige antibody. the results of this research indicated that the lower value for ige was detected in children at birth (x=3.s3 iu/ml), w...