BACKGROUND Brain-derived neurotrophic factor (BDNF) is implicated as a causal factor in major depression and is critical to placental development during pregnancy. Longitudinal data on BDNF across the perinatal period are lacking. These data are of interest given the potential implications for maternal mood and fetal growth, particularly among Black women who show ∼2-fold greater risk for deliv...

The purpose of the study is to show in which trimester of pregnancy is fatigue more common among working women, and whether or not there is any relationship between fatigue rate and educational level, income, etc. This is a longitudinal study. From the total number of patients who came to Zeinab University Hospital, 100 completed a demographics 50 item questionnaire and the numerical ratin...

Objective The aim of this study was to investigate the prevalence of abnormal vaginal microorganisms in pregnant women according to trimester, and to determine whether the presence of abnormal vaginal colonization is associated with higher risk of miscarriage or preterm delivery. Furthermore, we analyzed delivery outcomes according to individual microorganism species. Methods We included preg...

Background: To determine the association between pre-conception obesity and screening results of pre-natal and post-natal anxiety in women referred to the health centers of Tabriz, Iran. Methods: 62 obese (class 2-3) and 245 normal-weight women were enrolled in the first trimester of pregnancy through the cohort study and followed up 1 year after childbirth from December 2012 to January 2016. ...

Objectives: We investigated the auditory cognitive and behavioral functions during 2nd 3rd trimesters of pregnancy using event-related potentials (ERPs) different neuropsychology tests, respectively.
 Methods: The ERPs were studied by a 128-sensor net, PAS/COWA, WCST, ZCT, RAVLTIM/RAVLTDR/RAVLTTS, BDI tested for assessment. Total 39 subjects recruited control group (G1, n=15, non-pregnant)...

Type 1 and 2 diabetes decrease the frequencies and functional capacities of circulating angiogenic cells (CAC). Diabetes also elevates gestational complications. These observations may be interrelated. We undertook pilot studies to address the hypothesis that preconception diabetes deviates known gestational increases in CACs. Cross-sectional study of type 1 diabetic, type 2 diabetic and normog...

BACKGROUND Cytokines play an essential role in the regulation of immunological responses. Interleukin 15 (IL-15) is a glycoprotein secreted primarily by macrophages and monocytes. IL-15 plays a key role in the immunological response of the cellular type. OBJECTIVES The objective of this study was to evaluate changes in the concentration of interleukin 15 in amniotic fluid in the second and th...

Protein and nitrogen (N) accretion by the mother is a major adaptive response to pregnancy in humans and animals to meet the demands of the growing conceptus. Quantitative changes in whole body N metabolism were examined during normal pregnancy by measuring the rates of leucine N ( Q N) and carbon ( Q C) kinetics with the use of [1-13C,15N]leucine. Rate of synthesis of urea was measured by [15N...

BACKGROUND Evidence suggests that the hormonal milieu of pregnancy is an important determinant of subsequent cancer and other chronic diseases in both the mother and the offspring. Many of the existing maternity and birth cohorts include specimens drawn only once during pregnancy. How well a single blood specimen collected during a pregnancy characterizes exposure to these hormones throughout g...