A series of pentacyanoferrate complexes, N a3[F e (C N )5L ] /jH20 , where L = (C H 3) 2N H , (C 2H 5) 2N H , (C 2H 5)3N , (C 3H 7)2N H , (C 4H 9)2N H , (C 4H 9)3N and (C 6H 5)2N H were studied by Mössbauer and infrared spectroscopy. A ll the complexes exhibited two line spectra with A E Q = 0.73—1.92 mms“1 and <5 = —0.04—0.49 m m s '1 (w.r.t. SNP) and can be divided into two groups with well d...

The aerial parts of Tephrosia carrollii afforded two chromene chalcones. Their structures and stereochemistry were established by spectroscopic methods. The structure of oaxacacin was revised and confirmed by X-ray diffraction. In this paper, we describe the isolation of the chalcone known as "oaxacacin" and the new chalcone named epoxyobovatachalcone. The compound der. oaxacacin was found to b...

In the asymmetric unit of the title compound, C(16)H(11)FO(5)S, the 2H-chromene ring is essentially planar, with a maximum deviation of 0.040 (2) Å. The dihedral angle between the 2H-chromene ring and the 4-fluoro-phenyl ring is 2.17 (8)°. One of the sulfonamide O atoms is approximately coplanar with the benzene ring [C-C-S-O torsion angle = 166.00 (14)°], whereas the other O atom lies well bel...

The anion [Fe(2)(S(2)C(3)H(6))(CN)(CO)(4)(PMe(3))](-) (2(-)) is protonated by sulfuric or toluenesulfonic acid to give HFe(2)(S(2)C(3)H(6))(CN)(CO)(4)(PMe(3)) (2H), the structure of which has the hydride bridging the Fe atoms with the PMe(3) and CN(-) trans to the same sulfur atom. (1)H, (13)C, and (31)P NMR spectroscopy revealed that HFe(2)(S(2)C(3)H(6))(CN)(CO)(4)(PMe(3)) is stereochemically ...

Compound 1: H NMR (500 MHz, DMSO-d6) δ 11.64 (s, 1H), 8.73 (s, 4H), 8.57 (d, J = 1.4 Hz, 1H), 8.16 (dd, J = 8.9, 1.4 Hz, 1H), 7.81 (d, J = 8.5 Hz, 2H), 7.64 (d, J = 8.5 Hz, 2H), 6.99 (d, J = 8.9 Hz, 1H), 4.08 (t, J = 7.0 Hz, 2H), 3.28 (m, 2H), 1.69 (quin, J = 7.0 Hz, 2H), 1.33 (m, 8H), 0.86 (t, J = 6.8 Hz, 3H). C NMR (125 MHz, DMSO-d6) δ 162.6 (2xC = 0), 162.3 (2xC = 0), 158.9, 155.1, 151.9, 14...

A novel and efficient route for rapid access to indeno[1,2-c]azepin-3(2H)-ones is described, which proceeds through a palladium-catalyzed tandem reaction of 2-alkynylhalobenzene with 2-alkynylbenzamide in the presence of PPh(3) or PCy(3). The indeno[1,2-c]azepin-3(2H)-ones which incorporate both indene and unsaturated seven-membered ring lactam skeletons are obtained in good to excellent yields.

Several novel 6-thio-3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-based compounds containing an ω-(dialkylamino(heterocyclyl)]alkyl fragment were synthesized to examine their anticancer activity. Some of the 6-{[ω-(hetero-cyclyl)alkyl]thio}-3-R-2H-[1,2,4]triazino[2,3-c]quinazoline-2-ones (3.1-3.10) were obtained by the nucleophilic substitution of 6-[ω-halogenalkyl]thio-3-R-2H-[1,2,4]triazino...

THE TITLE COMPOUND (SYSTEMATIC NAME 7-oxo-3-phenyl-2,6-dioxabicyclo-[3.3.1]nonan-4-yl acetate), C(15)H(16)O(5), is a styryllactone derivative which was isolated from Goniothalamus macrophyllus. The mol-ecule has two fused rings consisting of a tetra-hydro-2H-pyran and a lactone ring, with the benzene ring and the acetyl group attached to the tetra-hydro-2H-pyran ring. The tetra-hydro-2H-pyran r...

Poliovirus type 2 Sabin mutants were selected for drug resistance and dependence by plating on HeLa cell monolayers in the presence of 3(2H)-isoflavene, a compound related to dichloroflavan, which prevents the shut-off of host translation and poliovirus RNA and protein synthesis. The drug-resistant mutants grew equally well in the presence and in the absence of the drug, while the drug-dependen...