Although gut microbiome dysbiosis has been associated with inflammatory bowel disease (IBD), the relationship between oral microbiota and IBD remains poorly understood. This study aimed to identify unique patterns in saliva from patients explore potential microbial markers for differentiating Crohn’s (CD) ulcerative colitis (UC). A prospective cohort recruited (UC: n = 175, CD: 127) healthy con...

Patterning of complicated animal body plans requires interactions between constituting cells, and signaling cascades play important roles in the interactions. Examples of some well-characterized signaling cascades include the Wnt family (Moon et al., 1997; Dierick and Bejsovec, 1999), the TGFβ family (Piek et al., 1999), the FGF family (Nugent and Iozzo, 2000; Ornitz, 2000) and the EGF family (...

One of the major challenges in pharmaceutical industry is search for new antimicrobial compounds that can replace antibiotics. Lactic acid bacteria (LAB) produce bacteriocin-like inhibitory substances (BLIS) have a bacteriostatic or bactericidal effect against different bacterial genera, including those responsible dental caries. Among pathological processes microbial etiology, caries stands ou...

OBJECTIVE Numerous studies have shown network assessments of social contact predict mortality in patients with coronary artery disease (CAD). Fewer studies have demonstrated an association between perceived social support and longevity in patient samples. It has been suggested that 1 of the mechanisms linking social support with elevated risk for mortality is the association between social supp...