The reference to ethnicity in the 2012 National Suicide Prevention Strategy for England (1) is mainly with regard to promoting mental health in Black and Minority Ethnic (BME) groups. However, there is little detailed information about any specific strategy to reduce suicide rates in BME groups. The Suicide Prevention Strategy and Action Plan for Northern Ireland has only one brief reference re...

background: boophilus tick is responsible for the transmission of some pathogens (types of germs) and the reduction of fertility in cattles. tropomyosin protein plays an important role in regulating actin function, immune and allergic reactions and vaccine production. objectives: accurate identification of antigenic determinants (epitopes) is difficult, time consuming and not economic, thus we ...

Factor XI deficiency is a rare bleeding diathesis found predominantly in Ashkenazi Jewish kindreds. A recent study of six Jewish patients identified three distinct mutations (Types I, II, and III) in the factor XI gene that were sufficient to fully define the genotypes of the patients. We have investigated 63 patients with factor XI deficiency and find overall allele frequencies of 44% for the ...

OBJECTIVE Ketosis-prone diabetes (KPD) comprises four subgroups based on the presence or absence of beta-cell autoantibodies (A+ or A-) and beta-cell functional reserve (beta+ or beta-). Genetic factors could contribute to their distinctive phenotypes. Our aim was to specify the role of HLA class II alleles associated with susceptibility or resistance to autoimmune type 1 diabetes in determinin...

Epithelial cells lining the inner surface of the intestinal epithelium are in direct contact with a lumenal environment that varies dramatically with diet. It has long been suggested that the intestinal epithelium can sense the nutrient composition of lumenal contents. It is only recently that the nature of intestinal nutrient-sensing molecules and underlying mechanisms have been elucidated. Th...

The fire ant Solenopsis invicta and its close relatives display an important social polymorphism involving differences in colony queen number. Colonies are headed by either a single reproductive queen (monogyne form) or multiple queens (polygyne form). This variation in social organization is associated with variation at the gene Gp-9, with monogyne colonies harboring only B-like allelic varian...