نتایج جستجو برای: 246
تعداد نتایج: 6545 فیلتر نتایج به سال:
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Mutations of TP53 may reach 70% - 85% in HNSCC patients without human papillomavirus (HPV) infection. Recurrence rate remains particularly high for HNSCC patients with mutations in the TP53 gene although patients are responsive to surgery, irradiation, and chemotherapy early in the treatment. p53-Reactivati...
Orthopoxvirus infections, such as smallpox, can lead to severe systemic disease and result in considerable morbidity and mortality in immunologically naïve individuals. Treatment with ST-246, a small-molecule inhibitor of virus egress, has been shown to provide protection against severe disease and death induced by several members of the poxvirus family, including vaccinia, variola, and monkeyp...
BACKGROUND The number of nurses able to independently prescribe medicines in England has risen steadily in recent years. AIM To evaluate the adequacy of nurses' educational preparation for independent prescribing and to describe nurses' experiences of their continuing professional development as prescribers in practice. DESIGN AND METHOD Postal questionnaire survey. PARTICIPANTS Random sa...
A DNA polymorphism in the coding region of coagulation factor IX-potentially valuable for carrier detection. pronetel diagnosis. and population studies-was described in 1 985. It had been discovered with monoclonal antibodies that distinguish between threonine and alanine as the 1 48th residue of the peptide. Its use as a diagnostic tool has been limited because threonine-containing factor IX (...
6 [226]. 6.0 [246]. 64 [71]. Absurdity [57]. Academia [163]. Academic [173]. Acceleration [67]. Accelerators [98]. Acceptance [114]. Access [145]. Achievements [77]. Acing [206]. Active [50, 171]. Active-Content [171]. ActiveState [246]. Activities [44, 101]. Ad [158]. Adaptable [73]. Address [8]. Adds [50, 246]. Adopt [114]. Advance [8]. Advances [7, 106, 120, 147, 176, 214]. Advantage [96]. A...
ST-246, a potent orthopoxvirus egress inhibitor, is safe and effective at preventing disease and death in studies of small-animal models involving challenge by several different pathogenic poxviruses. In this report, the antiviral efficacy of ST-246 in treatment of nonhuman primates infected with variola virus or monkeypox virus was assessed. The data indicate that oral dosing once per day with...
The protozoan intestinal parasite Cryptosporidium commonly infects cattle throughout the world and Iran. The present study was undertaken to determine the abundance and associated risk factors of Cryptosporidium infection in cattle herds of northwestern Iran. A total number of 246 fecal samples from 138 (56.1%) diarrheic (D) and 108 (43.9%) non-diarrheic (ND) cattle were rando...
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