porcine hepatocytes have been submitted for clinical trials as a “bridge” for liver transplantations in patients with fulminant hepatic failure. But the possibility of zoonosis is of concern and the use of xenogeneic cells for human therapy has severe practical limitations. Therefore, mass culture of human hepatocytes, about 10 cells, at high cell density in the bioreactor and their functional ...

Results We identified 6 children with AAV treated with rituximab (microscopic polyangeitis, n = 2, granulomatosis with polyangeitis, n = 2, unspecified vasculitis, n = 2). The age at onset ranged from 4 to 16 yrs. Treatment with rituximab consisted in 4 infusions of 375 mg/m; one patient received only 3 infusions. Mean duration of follow-up was 2.65 yrs. All patients achieved clinical remission...

6 Raubenheimer, D. and Simpson, S.J. (2004) Organismal stoichiometry: quantifying non-independence among food components. Ecology 85, 1203–1216 7 Simpson, S.J. et al. (2004) Optimal foraging when regulating intake of multiple nutrients. Anim. Behav. 68, 1299–1311 8 Hutchinson, G.E. (1957) Concluding remarks. Cold Spring Harb. Symp. Quant. Biol. 22, 415–427 9 Gates, D.M. (1980) Biophysical Ecolo...

We use QCD sum rules to study mass spectra of $P$-wave charmed baryons the $SU(3)$ flavor $\mathbf{6}_F$. also light-cone their $S$- and $D$-wave decays into ground-state together with light pseudoscalar vector mesons. work within framework heavy quark effective theory, we consider mixing effect. Our results can explain many excited as a whole, including $\Sigma_c(2800)^0$, $\Xi_c(2923)^0$, $\X...

Abstract Since the hypervelocity stars were discovered in Milky Way, various mechanisms have been proposed to explain these runaway stars. Up now, however, dominant ejected mechanism of is still unclear. As largest and closest face-on satellite galaxy Large Magellanic Cloud (LMC) serves as a good target, allowing us study this issue. Based on high-precision astrometric parameters provided by Ga...

The mutator phenotype hypothesis was postulated more than 40 years ago. It was based on the multiple enzymatic steps required to precisely replicate the 6 billion bases in the human genome each time a normal cell divides. A reduction in this accuracy during tumor progression could be responsible for the striking heterogeneity of malignant cells within a tumor and for the rapidity by which cance...

Student Member, Institute of Industrial Engineers. E-mail: [email protected]. Telephone: (404) 8229746. Fax: (404) 894-2301. E-mail: [email protected]. Telephone: (404) 894-2361. Fax: (404) 894-2301. Member, Institute of Industrial Engineers. E-mail: [email protected]. Telephone: (404) 894-2365. Fax: (404) 894-2301. Member, Institute of Industrial Engineers, and corresponding author. E-mail:...