نتایج جستجو برای: 2 azetidinones

تعداد نتایج: 2525267  

2009
Mrunmayee P. Toraskar Vilasrao J. Kadam Vithal M. Kulkarni

Ethyl-1H-benzotriazol-1-acetate 2 was prepared by reacting 1H-benzotriazole 1 in alcohol with ethyl bromoacetate in presence of anhydrous potassium carbonate, which was treated with hydrazine hydrate under reflux for 1824 hours to obtain the intermediate 1H-benzotriazole-1-acetic acid hydrazide 3. This compound on Schiff’s reaction with aromatic aldehydes in presence of solvent mixture yielded ...

Journal: : 2023

The current study involved synthesis of several new N-Substituted -
 3- chloro -2- azetidinones for 2,4-Diamino-6-phenyl-1,3,5-triazine by two
 steps. first step includes preparation Schiff bases (Al-A6) by
 condensation 2,4-Diamino-6-pheny]-1,3,5-triazine with many substituted
 aldehydes, then the second six azetidinone
 compounds (B1-B6) reaction acetyl chloride the&#...

Journal: :European journal of medicinal chemistry 2010
Miriam Carr Lisa M Greene Andrew J S Knox David G Lloyd Daniela M Zisterer Mary J Meegan

The synthesis and study of the structure-activity relationships of a series of rigid analogues of combretastatin A-4 are described which contain the 1,4-diaryl-2-azetidinone (β-lactam) ring system in place of the usual ethylene bridge present in the natural combretastatin stilbene products. The 1,4-diaryl-2-azetidinones are unsubstituted at C-3, or contain methyl substituent(s) at C-3. The most...

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