Some of fused dihydrobenzo [4,5]imidazo [1,2-a] pyrmido [5,4-e] pyrmidin-3(4H)-amine  derivatives were synthesized,  theses derivatives derived from 4-amino-2-(4-chloro or bromophenyl) -1,2-dihydropyrimido[1,2-a] benzimidazole-3-carbonitrile (4,5), which prepared by reaction 1H-benzimidazol-2-amine (1) and p-chlorobenzaldehyde p-bromobenzaldehyde (2)  and malononitrile (3)...

Mukesh C. Sharma Dept. of Pharmaceutical Sciences, Dr.Hari Singh Gour University Sagar (M.P) 470003 India Department of Chemistry Yadhunath Mahavidyalya Bhind (M.P) 477001 India Email: [email protected] Abstract A new series of non peptide angiotensin (A-II) receptor antagonist has been prepared. This N-(biphenyl methyl) imidazoles e.g. Some new 4'-{5-amino2-[2-substituted-phenylamino)-ph...

BACKGROUND The majority of well-known inhibitors are organic compounds containing multiple bonds and heteroatoms, such as O, N or S, which allow adsorption onto the metal surface. These compounds can adsorb onto the metal surface and block active surface sites, reducing the rate of corrosion. RESULTS A comparative theoretical study of three benzimidazole isomers, benzimidazole (BI), 2-methylb...

In the title compound, [Cu(NO(3))(2)(C(8)H(9)N(3))(2)], the Cu(II) atom, lying on an inversion center, has a distorted octa-hedral coordination environment defined by four N atoms from two chelating 2-amino-methyl-1H-benzimidazole ligands and two O atoms from two monodentate nitrate anions. In the crystal, N-H⋯O hydrogen bonds link the complex mol-ecules into a three-dimensional network. An int...

Several substituted-benzimidazole 3-(4-{5-Amino-6-fluoro-1-[2'-(1H-tetrazole-5-yl)-biphenyl-4ylmethyl]-1H-benzoimidazol-2-yl}-phenyl) -2-(substituted)thiazolidin-4-one were synthesized by condensation of various steps with various substituted aryl aldehydes reaction. Elemental analysis, IR, 1HNMR and mass spectral data confirmed the structure of the newly synthesized compounds. Synthesized and ...

We report synthesis of novel series of amino alcohol derivatives of 2-methyl benzimidazole. These compounds have been synthesized by epoxide ring opening of 2-methyl benzimidazole with different substituted cyclic amines. These synthesized compounds have been characterized using IR, H NMR and ES-MS spectral data together with their melting point. These compounds (4a-4o) were evaluated for their...

Benzimidazole is one of the most important heterocyclic groups manifesting various biological properties, such as antibacterial, antifungal, antimicrobial, antiprotozoal and antihelmintic activities. Several benzimidazole derivatives are also active as inhibitors of type I DNA topoisomerases. In this study, three 1H-benzimidazole derivatives with different electronic characteristics at position...