The assessment of primary calibrator purity is critical for establishing traceability to the International System Units (SI). Recently, quantitative nuclear magnetic resonance (qNMR) has been used as a determination method reference material development, and many related measurement techniques have designed acquire accurate reliable results. This review introduces recent advances in these (incl...

Two new 5-deoxyflavonoids, 7,2',3',4'-tetramethoxyflavone (1) and 7,2',3',4'-tetramethoxyflavanone (2) together with a known flavone 7,4'-dimethoxy-3'-hydroxyflavone (3) were isolated from the whole plant of Calliandra inermis. The structures of these new compounds were elucidated by high resolution electron impact mass spectrometry (HR-EI-MS) and 1D and 2D-NMR spectral studies including 1H-1H ...

This report presents the backbone assignments and the secondary structure determination of the A domain of the Escherichia coli mannitol transport protein, enzyme-IImtl. The backbone resonances were partially assigned using three-dimensional heteronuclear 1H NOE 1H-15N single-quantum coherence (15N NOESY-HSQC) spectroscopy and three-dimensional heteronuclear 1H total correlation 1H-15N single-q...

The chemical structure of the new angucycline antibiotic landomycin A has been elucidated via chemical and spectroscopic methods, in particular by 2D NMR correlation spectroscopy, e.g., 1H, 1H-COSY, 13C, 1H-COSY, correlation spectroscopy via long-range-couplings and heteronuclear multiple bond connectivity spectroscopy sequences. The spectroscopic investigations were carried out principally wit...

Lipid extracts of plasma were studied by 31P and 1H NMR spectroscopy at 9.4 T. Signals recorded on lipid mixtures were assigned to different lipid classes using a data base built with two-dimensional 1H COSY spectra of seven standard lipids. Signals unique to glycerophospholipids, sphingolipids, and triacylglycerols were identified. 31P and 1H NMR spectroscopy was used to study qualitative and ...

an efficient and simple one-pot approach for the synthesis of 3,4-dihydropyrimidin-2-(1h)-one derivatives using antimony trichloride (sbcl3) as a mild catalyst by means of three-component biginelli reaction between β-keto esters, aldehyde derivatives and urea/thiourea under thermal and solvent-free conditions with excellent yields and short reaction times is reported. this methodology offers se...

we report a 73-year-old woman with primary left atrial rhabdomyosarcoma and its 1h mr spectroscopy (mrs) findings. the tumor showed a 2.8 cm sized lesion in the posteroinferior atrial wall on mri. 1h mr spectra were acquired using a point-resolved spectroscopy (press) sequence with electrocardiographic (ecg) gating and respiratory motion. the use of 1h-mrs allowed the quantification of triglyce...

Abstract Quantitative nuclear magnetic resonance (qNMR) is considered as a powerful tool for multicomponent mixture analysis well the purity determination of single compounds. Special attention currently paid to training operators and study directors involved in qNMR testing. To assure that only qualified personnel are used sample preparation at our GxP-accredited laboratory, weighing test was ...

In this study, perfluorinated phosphonic acid modifications were utilized to modify zinc oxide (ZnO) nanoparticles because they create a more stable surface due to the electronegativity of the perfluoro head group. Specifically, 12-pentafluorophenoxydodecylphosphonic acid, 2,3,4,5,6-pentafluorobenzylphosphonic acid, and (1H,1H,2H,2H-perfluorododecyl)phosphonic acid have been used to form thin f...

Gülin Öz, PhD Jeffry R. Alger, MPhil, PhD Peter B. Barker, MPhil Robert Bartha, PhD Alberto Bizzi, MD Chris Boesch, MD, PhD Patrick J. Bolan, PhD Kevin M. Brindle, DPhil, Cristina Cudalbu, PhD Alp Dinçer, MD Ulrike Dydak, PhD Uzay E. Emir, PhD Jens Frahm, PhD Ramón Gilberto González, MD, PhD Stephan Gruber, PhD Rolf Gruetter, PhD Rakesh K. Gupta, MD Arend Heerschap, PhD Anke Henning, PhD Hoby P...