نتایج جستجو برای: 186re
تعداد نتایج: 57 فیلتر نتایج به سال:
R ecent pre-clinical and clinical studies indicate that irradiation within the dose range of 15 to 30 Gy can reduce the rate of restenosis in patients who have undergone an angioplasty (Nath 1999, King 1998). Several delivery systems of intravascular brachytherapy have been developed to deliver doses within this rang with minimal normal tissue toxicity. One of the possible intravascular irradia...
Objectives: The goals of this investigation are to determine whether commercially available dose calibrators can be used to measure the activity of -emitting radionuclides used in pain palliation and to establish whether manufacturer-supplied calibration factors are appropriate for this purpose. Methods: Six types of commercially available dose calibrators were studied. Dose calibrator response...
UNLABELLED From December 1999 until July 2001, a phase I dose escalation study was performed with (186)Re-labeled bivatuzumab, a humanized monoclonal antibody against CD44v6, on patients with inoperable recurrent or metastatic head and neck cancer. The aim of the trial was to assess the safety and tolerability of intravenously administered (186)Re-bivatuzumab and to determine the maximum tolera...
Rhenium-186 (tin)-labeled hydroxyethylidene diphosphonate (186Re-labeled HEDP) was evaluated in 27 men with progressive androgen-independent prostate cancer and bone metastases. Administered activities ranged from 1251 to 4336 MBq (33.8-117.2 mCi). The primary objectives were to assess tumor targeting, normal organ dosimetry, and safety. Antitumor effects were assessed by posttherapy changes in...
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