نتایج جستجو برای: 184 zn
تعداد نتایج: 48038 فیلتر نتایج به سال:
BACKGROUND miRNA-184 is an oncogene in human hepatocellular carcinoma but acts as a tumor suppressor in tongue squamous cell carcinoma. Studies have shown that miR-184 was down-regulated in glioma and TNFα-induced protein 2 (TNFAIP2) was closely related to tumorigenesis. This study aimed to determine the functions of miR-184 in glioma and the mechanisms of miRNA-184-TNFAIP2 mediated glioma prog...
Human microRNA 184 (miR-184) is overexpressed in squamous cell carcinoma (SCC) of the tongue. In vitro inhibition of miR-184 levels could induce apoptosis and hinder proliferation of tongue SCC cells. Patients with tongue SCC have high plasma miR-184 levels. Plasma miR-184 is likely associated with the tumor load. Surgical removal of the primary tumor reduced plasma miR-184 levels significantly...
RATIONALE PKP2, encoding plakophilin 2 (PKP2), is the most common causal gene for arrhythmogenic cardiomyopathy. OBJECTIVE To characterize miRNA expression profile in PKP2-deficient cells. METHODS AND RESULTS Control and PKP2-knockdown HL-1 (HL-1(Pkp2-shRNA)) cells were screened for 750 miRNAs using low-density microfluidic panels. Fifty-nine miRNAs were differentially expressed. MiR-184 wa...
PURPOSE A mutation miR-184(+57C>T) in the seed region of miR-184 (encoded by MIR184 [MIM*613146]) results in familial severe keratoconus combined with early-onset anterior polar cataract and endothelial dystrophy, iris hypoplasia, congenital cataract, and stromal thinning (EDICT) syndrome (MIM#614303). In order to investigate the phenotypic spectrum resulting from MIR184 mutation, MIR184 was se...
BACKGROUND Early metastasis of osteosarcoma (OS) is highly lethal and responds poorly to drug and radiation therapies. MicroRNAs (miRNAs) are a class of small noncoding RNAs that modulate gene expression at the post-transcriptional level. However, the detailed functions of specific miRNAs are not entirely understood. The aim of the present study was to investigate the role of miR-184 as a media...
We report a high-resolution gas-phase UPS spectrum of zinc phthalocyanine (ZnPc) together with a detailed analysis of the vibronic structure of the first ionization band, showing that presents the lowest value of the intramolecular reorganization energy experimentally reported for a molecular organic semiconductor.
Background: Given the importance of vegetables in the food pyramid, their safety is very important from view point of public health. Vegetable contamination by heavy metals can lead to bioaccumulation of these toxic and disease-causing elements in the body of consumers. Therefore, in this study, the concentration of some heavy metals, including lead (Pb), cadmium (Cd), zinc (Zn) and copper (Cu)...
Local structures around metal atoms in Hi and Zn substituted 132-hydroxy-bacteriochlorophyll a (Ni-HOB, and Zn-HOB) with and without insertion into the accessory bacteriochlorophyll a (BChla) sites in Rhodobacter sphaeroides photosynthetic reaction centers (RC) are studied using X-ray absorption spectroscopy. The penta-coordination of Ni-HOB and Zn-HOB in the RC is similar to that of BChl a in ...
It is commonly alleged that a substantial proportion of lawsuits are frivolous and are filed only for their nuisance value. This paper models settlement bargaining in the presence of frivolous suits as a game of asymmetric information, where the plaintiff knows the true merits of his claim, and the defendant does not, apart from any inferences he can draw from the fact of suit. When there is fr...
Kojima and Manea (2010) present two characterizations of when an allocation rule corresponds to the agent-proposing deferred acceptance algorithm for some substitutable priority rule of the objects being assigned. Building on their results we characterize when an allocation rule is outcome equivalent to the deferred acceptance algorithm for every substitutable priority rule. In particular, an a...
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