The present study examined the effect of long-term treatment with amlodipine and MCI-154 (a Ca2+ sensitizer) on progressive cardiac dysfunction and microvasculature in the dilated cardiomyopathic (DCM) hamster heart. After treatment of DCM hamsters (Bio 53.58) with amlodipine or MCI-154 for 15 wk from the age of 5 wk, amlodipine and MCI-154 were found to cause an increase in left ventricular pe...

PURPOSE Good continence is reported after ileal pouch-anal reconstruction, but little is known about long-term durability. Our aim was to prospectively evaluate long-term function in these patients. METHODS Surveys were sent to 235 patients who had returned similar surveys in 1992; paired data were then compared with contingency tables. RESULTS A total of 154 patients (66 percent) returned ...

BACKGROUND AND PURPOSE Iceland is an island in the North Atlantic with ≈319 000 inhabitants. The study determines the incidence of first stroke in the adult population of Iceland during 12 months, which has not been previously reported in the entire Icelandic population. METHODS The study population consisted of all residents of Iceland, aged ≥ 18 years, during the 12-month study period. Case...

BACKGROUND The authors conducted a study to examine the antibiotic prescribing practices of general and pediatric dentists in the management of odontogenic infections in children. METHODS The authors relied on a cross-sectional study design to assess the antibiotic prescribing practices of general and pediatric dentists in North Carolina. The survey instrument consisted of five clinical case ...

With the negative results of the cyclic AMP-dependent positive inotropic agents in clinical trials, great interest has been focused on the development of agents that directly activate cardiac myofilaments. These drugs are called “Ca2+ sensitizers”; they are expected to represent a possible new pharmacological approach to the therapy of chronic heart failure. MCI-154 is one of the most powerful ...

SUMMARY During 2 years, 212 patients with PID and 160 women with no sign of PIO (as control group) were selected for the detection of aerobic an<l anaerobic bacteria and possible cause of the disease. Specimens from 58 patients and 60 controls were taken by laparoscopy and laparotomy, 154 patients and 100 controls by swabs from endocervical canal. From laparoscopy and laparotomy group(58) 9 ...

Part 2. Computability Theory: Very Powerful Models 15 7. Turing Machines: 1/28/14 15 8. Recognizability, Decidability, and Reductions: 1/30/14 18 9. Reductions, Undecidability, and the Post Correspondence Problem: 2/4/14 21 10. Oracles, Rice’s Theorem, the Recursion Theorem, and the Fixed-Point Theorem: 2/6/14 23 11. Self-Reference and the Foundations of Mathematics: 2/11/14 26 12. A Universal ...